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Gene Expression Data
Assay Details
Assay
Reference: J:54206 Jung HS, et al., Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae. Mech Dev. 1999 Mar;81(1-2):179-82
Assay type: RNA in situ
MGI Accession ID: MGI:2671104
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe22
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1D: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: lateral lingual swelling Weak Regionally restricted 1D Expression is absent in the median sulcus.
Specimen 1H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lateral lingual swelling epithelium Present Graded 1H Highest expression is at the periphery with an apparent down-regulation in the central area of the tongue.
TS19: median lingual swelling epithelium Present Graded 1H Highest expression is at the periphery with an apparent down-regulation in the central area of the tongue.
TS19: dental placode Present 1H Expression is in the developing incisor and molar tooth buds.
Specimen 1L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lateral lingual swelling epithelium Weak 1L
TS20: median lingual swelling epithelium Weak 1L
Specimen 2D: embryonic day 11.0 (more )
Note: Embryos were embedded in a gelatin/albumin mixture and 80-100 micron vibratome sections were cut.
Structure Level Pattern Image Note
TS18: lateral lingual swelling epithelium Strong Regionally restricted 2D Expression is in the dorsal epithelium.
TS18: median lingual swelling epithelium Strong Regionally restricted 2D Expression is in the dorsal epithelium.
TS18: lateral lingual swelling mesenchyme Weak 2D
TS18: median lingual swelling mesenchyme Weak 2D
Specimen 2H: embryonic day 12.5 (more )
Note: Embryos were embedded in a gelatin/albumin mixture and 80-100 micron vibratome sections were cut.
Structure Level Pattern Image Note
TS20: lateral lingual swelling epithelium Trace Regionally restricted 2H Expression is in the dorsal epithelium.
TS20: median lingual swelling epithelium Trace Regionally restricted 2H Expression is in the dorsal epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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