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Gene Expression Data
Assay Details
Assay
Reference: J:54206 Jung HS, et al., Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae. Mech Dev. 1999 Mar;81(1-2):179-82
Assay type: RNA in situ
MGI Accession ID: MGI:2671102
Gene symbol: Bmp2
Gene name: bone morphogenetic protein 2
Probe: Bmp2 probe11
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: lateral lingual swelling Weak Regionally restricted 1B Expression is absent in the median sulcus.
Specimen 1F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lateral lingual swelling epithelium Strong Graded 1F Highest expression is at the periphery with an apparent down-regulation in the central area of the tongue.
TS19: median lingual swelling epithelium Strong Graded 1F Highest expression is at the periphery with an apparent down-regulation in the central area of the tongue.
TS19: dental placode Present 1F Expression is in the developing incisor and molar tooth buds.
Specimen 1J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lateral lingual swelling epithelium Present Spotted 1J Expression in spots in the posterior part of the tongue and weakly in rows of spots running parallel to the median sulcus in the anterior part.
TS20: median lingual swelling epithelium Present Spotted 1J Expression in spots in the posterior part of the tongue and weakly in rows of spots running parallel to the median sulcus in the anterior part.
Specimen 1N: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tongue epithelium Present Spotted 1N The expression is in punctate patches at regular intervals often symmetrically located in rows at both sides of the median sulcus.
Specimen 1Q: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tongue epithelium Present Spotted 1Q
Specimen 1T: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tongue epithelium Weak Spotted 1T There are fewer spots at this age in the anterior part of the tongue.
Specimen 2B: embryonic day 11.0 (more )
Note: Embryos were embedded in a gelatin/albumin mixture and 80-100 micron vibratome sections were cut.
Structure Level Pattern Image Note
TS18: lateral lingual swelling epithelium Strong Regionally restricted 2B Expression is in the dorsal epithelium.
TS18: median lingual swelling epithelium Strong Regionally restricted 2B Expression is in the dorsal epithelium.
Specimen 2F: embryonic day 12.5 (more )
Note: Embryos were embedded in a gelatin/albumin mixture and 80-100 micron vibratome sections were cut.
Structure Level Pattern Image Note
TS20: lateral lingual swelling epithelium Present Regionally restricted 2F Expression is localized in two areas in the dorsal epithelium adajcent to the median sulcus.
TS20: median lingual swelling epithelium Present Regionally restricted 2F Expression is localized in two areas in the dorsal epithelium adajcent to the median sulcus.
Specimen 2J: embryonic day 13.5 (more )
Note: Embryos were embedded in a gelatin/albumin mixture and 80-100 micron vibratome sections were cut.
Structure Level Pattern Image Note
TS21: tongue epithelium Present Spotted 2J Expression is in the dorsal epithelium.
Specimen 2N: embryonic day 15.5 (more )
Note: Embryos were embedded in a gelatin/albumin mixture and 80-100 micron vibratome sections were cut.
Structure Level Pattern Image Note
TS23: tongue epithelium Weak Regionally restricted 2N Expression is in the peripheral cells of the papillae.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory