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Gene Expression Data
Assay Details
Assay
Reference: J:54206 Jung HS, et al., Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae. Mech Dev. 1999 Mar;81(1-2):179-82
Assay type: RNA in situ
MGI Accession ID: MGI:2671101
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe34
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: lateral lingual swelling Weak Regionally restricted 1A Expression is absent in the median sulcus.
Specimen 1E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lateral lingual swelling epithelium Present Graded 1E Highest expression is at the periphery with an apparent down-regulation in the central area of the tongue.
TS19: median lingual swelling epithelium Present Graded 1E Highest expression is at the periphery with an apparent down-regulation in the central area of the tongue.
TS19: dental placode Present 1E Expression is in the developing incisor and molar tooth buds.
Specimen 1I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lateral lingual swelling epithelium Present Spotted 1I Expression in spots in the posterior part of the tongue and weakly in rows of spots running parallel to the median sulcus in the anterior part.
TS20: median lingual swelling epithelium Present Spotted 1I Expression in spots in the posterior part of the tongue and weakly in rows of spots running parallel to the median sulcus in the anterior part.
Specimen 1M: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tongue epithelium Present Spotted 1M The expression is in punctate patches at regular intervals often symmetrically located in rows at both sides of the median sulcus.
Specimen 1P: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tongue epithelium Present Spotted 1P
Specimen 1S: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tongue epithelium Present Spotted 1S
Specimen 2A: embryonic day 11.0 (more )
Note: Embryos were embedded in a gelatin/albumin mixture and 80-100 micron vibratome sections were cut.
Structure Level Pattern Image Note
TS18: lateral lingual swelling epithelium Strong Regionally restricted 2A Expression is in the dorsal epithelium.
TS18: median lingual swelling epithelium Strong Regionally restricted 2A Expression is in the dorsal epithelium.
Specimen 2E: embryonic day 12.5 (more )
Note: Embryos were embedded in a gelatin/albumin mixture and 80-100 micron vibratome sections were cut.
Structure Level Pattern Image Note
TS20: lateral lingual swelling epithelium Present Regionally restricted 2E Expression is in the dorsal epithelium with stronger expression in the medial area than in the lateral area.
TS20: median lingual swelling epithelium Present Regionally restricted 2E Expression is in the dorsal epithelium with stronger expression in the medial area than in the lateral area.
Specimen 2I: embryonic day 13.5 (more )
Note: Embryos were embedded in a gelatin/albumin mixture and 80-100 micron vibratome sections were cut.
Structure Level Pattern Image Note
TS21: tongue epithelium Present Spotted 2I Expression is in the dorsal epithelium.
Specimen 2M: embryonic day 15.5 (more )
Note: Embryos were embedded in a gelatin/albumin mixture and 80-100 micron vibratome sections were cut.
Structure Level Pattern Image Note
TS23: tongue epithelium Very strong Spotted 2M
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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