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Gene Expression Data
Assay Details
Assay
Reference: J:78684 Baumer N, et al., Pax6 is required for establishing naso-temporal and dorsal characteristics of the optic vesicle. Development. 2002 Oct;129(19):4535-45
Assay type: RNA in situ
MGI Accession ID: MGI:2386634
Gene symbol: Foxd1
Gene name: forkhead box D1
Probe: Hfhbf2 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen +/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present Regionally restricted 6B Expression is present in the temporal neuroretina.
Specimen Pax6-/-: embryonic day 12.5; Pax6tm1Pgr/Pax6tm1Pgr (more )
Structure Level Pattern Image Note
TS20: eye Absent 6D There is no expression in the optic vesicle.
TS20: head mesenchyme Present Regionally restricted 6D Expression is present in the head mesenchyme surrounding the eye.
Specimen Not shown: embryonic day 12.5; Pax6tm2Pgr/Pax6tm2Pgr, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: retina Weak Regionally restricted Expression can only be detected in the distalmost tip of the retina.
Specimen aCre;Pax6flox/flox: embryonic day 14.5; Pax6tm2Pgr/Pax6tm2Pgr, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: retina Absent 6F
TS22: head mesenchyme Present 6F
TS22: brain dura mater Present Regionally restricted 6F Expression is present in the dura mater surrounding the optic nerve.
Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: neural retinal epithelium Strong Regionally restricted There is strong expression in the temporal neuroretina.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory