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Gene Expression Data
Assay Details
Assay
Reference: J:78220 Zhang Z, et al., Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis. Development. 2002 Sep;129(17):4135-46
Assay type: RNA in situ
MGI Accession ID: MGI:2383972
Gene symbol: Bmp2
Gene name: bone morphogenetic protein 2
Probe: Bmp2 cDNA7
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: palatal shelf epithelium Present Regionally restricted 2G Expression in epithelium and mesenchyme of anterior region of palatal shelves.
TS20: palatal shelf mesenchyme Present Regionally restricted 2G Expression in epithelium and mesenchyme of anterior region of palatal shelves.

Specimen 2H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf epithelium Present Regionally restricted 2H Expression in epithelium and mesenchyme of anterior region of palatal shelves.
TS21: palatal shelf mesenchyme Present Regionally restricted 2H Expression in epithelium and mesenchyme of anterior region of palatal shelves.

Specimen 2I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf Absent 2I No expression in posterior palate.

Specimen 3G: embryonic day 12.5; Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS20: palatal shelf Present 3G Expression in mutant palatal shelf.

Specimen 3H: embryonic day 13.5; Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS21: palatal shelf epithelium Present 3H Expression downregulated in epithelium and mesenchyme of mutant palate.
TS21: palatal shelf mesenchyme Present 3H Expression downregulated in epithelium and mesenchyme of mutant palate.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory