Gene Expression Data
Assay Details
Assay
|
Reference:
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J:75943
Laurikkala J, et al., Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar. Development. 2002 May;129(10):2541-53
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2180522
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Gene symbol:
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Edar
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Gene name:
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ectodysplasin-A receptor
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Probe:
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dl probe
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
Not shown:
embryonic day 11.0
(more )
Note: This specimen was from the back.
Specimen
Not shown:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 11.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
This specimen was from the back.
|
Specimen
1B:
embryonic day 12.0
(more )
Note: This specimen was from the back.
Specimen
1B:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 12.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
This specimen was from the back.
|
Specimen
1D:
embryonic day 14.0
(more )
Specimen
1D:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 14.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: skin |
Present |
Patchy |
1D
|
There is intense expression in the placodes; expression is downregulated in the rest of the ectoderm.
|
Specimen
1H:
postnatal day 0
(more )
Specimen
1H:
(close )
Genetic Background:
|
NMRI
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: hair follicle |
Very strong |
|
1H
|
Expression is present in the bulb of stage 3-6 hair follicles.
|
Specimen
5I:
embryonic day 13.0
(more )
Specimen
5I:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 13.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: skin |
Present |
Uniform |
5I
|
Expression is present throughout the epithelium.
|
Specimen
5J:
(close )
Genetic Background:
|
involves: 129S2/SvPas
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Mutant Allele(s):
|
Lef1tm1Rug/Lef1tm1Rug
|
Age:
|
embryonic day 13.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: skin |
Present |
Uniform |
5J
|
Expression is present throughout the epithelium.
|
Specimen
5K:
embryonic day 17.0
(more )
Specimen
5K:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 17.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS25: hair bulb |
Very strong |
|
5K
|
There is intense expression in the bulbs of developing tylotrich hair follicles.
|
Specimen
5L:
(close )
Genetic Background:
|
involves: 129S2/SvPas
|
Mutant Allele(s):
|
Lef1tm1Rug/Lef1tm1Rug
|
Age:
|
embryonic day 17.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS25: hair follicle |
Present |
|
5L
|
There is intense expression in the bulbs of developing tylotrich hair follicles.
|
Specimen
Not shown:
embryonic day 17.0
(more )
Specimen
Not shown:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 17.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS25: skin |
Present |
Regionally restricted |
|
Expression is present in the initiated epithelial placodes of the awl hairs.
|
Specimen
7A:
embryonic day 15.0
(more )
Specimen
7A:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: skin |
Present |
Regionally restricted |
7A
|
Expression is present in the basal epithelium of the placodes of the first wave of tylotrich hairs found on the back.
|
Specimen
7B:
embryonic day 15.0; EdaTa/ EdaTa
(more )
Specimen
7B:
(close )
Genetic Background:
|
B6CBACa Aw-J/A-EdaTa/J-XO
|
Mutant Allele(s):
|
EdaTa/EdaTa
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: skin |
Present |
Regionally restricted |
7B
|
The placodes have not been initiated, so expression is present throughout the ectoderm.
|
Specimen
7C:
embryonic day 17.0
(more )
Specimen
7C:
(close )
Genetic Background:
|
NMRI
|
Age:
|
embryonic day 17.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS25: hair bulb |
Very strong |
|
7C
|
There is intense expression in the bulbs of developing tylotrich hair follicles.
|
TS25: skin |
Present |
Regionally restricted |
7C
|
Expression is present in the placodes of awl follicles.
|
Specimen
7D:
embryonic day 17.0; EdaTa/ EdaTa
(more )
Specimen
7D:
(close )
Genetic Background:
|
B6CBACa Aw-J/A-EdaTa/J-XO
|
Mutant Allele(s):
|
EdaTa/EdaTa
|
Age:
|
embryonic day 17.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS25: skin |
Very strong |
Regionally restricted |
7D
|
There is intense expression in the placodes of awl follicles.
|
|