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Gene Expression Data
Assay Details
Assay
Reference: J:75946 Kanai-Azuma M, et al., Depletion of definitive gut endoderm in Sox17-null mutant mice. Development. 2002 May;129(10):2367-79
Assay type: RNA in situ
MGI Accession ID: MGI:2180039
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA2
Probe preparation: Antisense RNA
Results
Specimen 4K +/-: embryonic day 8.5; Sox17tm1Ysk/Sox17+ (more )
Structure Level Pattern Image Note
TS13: gut endoderm Present 4K +/- Expression is present in the definitive gut endoderm of the fore, mid, and hindgut.
TS13: notochord Present 4K +/-
Specimen 4K -/-: embryonic day 8.5; Sox17tm1Ysk/Sox17tm1Ysk (more )
Structure Level Pattern Image Note
TS13: hindgut diverticulum endoderm Absent 4K -/- Expression was absent from the posterior endoderm.
TS13: midgut endoderm Absent 4K -/- Expression was absent from the posterior endoderm.
TS13: notochord Present 4K -/-
Specimen 4L +/-: embryonic day 8.5; Sox17tm1Ysk/Sox17+ (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present 4L +/-
Specimen 4L -/-: embryonic day 8.5; Sox17tm1Ysk/Sox17tm1Ysk (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Weak 4L -/-
Specimen 4M +/-: embryonic day 8.5; Sox17tm1Ysk/Sox17+ (more )
Structure Level Pattern Image Note
TS13: hindgut diverticulum endoderm Present 4M +/- Expression was present in the posterior endoderm.
TS13: midgut endoderm Present 4M +/- Expression was present in the posterior endoderm.
TS13: notochord Present 4M +/-
Specimen 4M -/-: embryonic day 8.5; Sox17tm1Ysk/Sox17tm1Ysk (more )
Structure Level Pattern Image Note
TS13: hindgut diverticulum endoderm Absent 4M -/- Expression was absent from the posterior endoderm.
TS13: midgut endoderm Absent 4M -/- Expression was absent from the posterior endoderm.
TS13: notochord Present 4M -/-
Specimen 4N +/-: embryonic day 9.5; Sox17tm1Ysk/Sox17+ (more )
Structure Level Pattern Image Note
TS15: gut Present Regionally restricted 4N +/- Expression is present in the definitive endoderm of the fore, mid, and hindgut.
TS15: notochord Present 4N +/-
Specimen 4N -/-: embryonic day 9.5; Sox17tm1Ysk/Sox17tm1Ysk (more )
Structure Level Pattern Image Note
TS15: foregut Weak Regionally restricted 4N -/- There is low expression in the definitive foregut endoderm.
TS15: hindgut Absent 4N -/- Expression is absent from the mid and hindgut epithelia.
TS15: midgut Absent 4N -/- Expression is absent from the mid and hindgut epithelia.
TS15: notochord Present 4N -/-
Specimen 4O +/-: embryonic day 9.5; Sox17tm1Ysk/Sox17+ (more )
Structure Level Pattern Image Note
TS15: foregut Present Regionally restricted 4O +/- Expression is present in the definitive foregut endoderm.
TS15: notochord Present 4O +/-
Specimen 4O -/-: embryonic day 9.5; Sox17tm1Ysk/Sox17tm1Ysk (more )
Structure Level Pattern Image Note
TS15: foregut Weak Regionally restricted 4O -/- There is low expression in the definitive foregut endoderm.
TS15: notochord Present 4O -/-
Specimen 4P +/-: embryonic day 9.5; Sox17tm1Ysk/Sox17+ (more )
Structure Level Pattern Image Note
TS15: midgut Present Regionally restricted 4P +/- Expression is present in the definitive midgut endoderm.
TS15: notochord Present 4P +/-
Specimen 4P -/-: embryonic day 9.5; Sox17tm1Ysk/Sox17tm1Ysk (more )
Structure Level Pattern Image Note
TS15: hindgut Absent 4P -/- Expression is absent from the mid and hindgut epithelia.
TS15: midgut Absent 4P -/- Expression is absent from the mid and hindgut epithelia.
TS15: notochord Present 4P -/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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