Gene Expression Data
Assay Details
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Assay
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Reference:
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J:74631
Tian E, et al., Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol. 2002 Feb 15;242(2):204-23
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2179003
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Gene symbol:
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Six3
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Gene name:
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sine oculis-related homeobox 3
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Probe:
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Six3 probe2
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
4E:
embryonic day 9.5
(more  )
Specimen
4E:
(close  )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
4F:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Mutant Allele(s):
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Otx2tm1Sia/Otx2tm4Sia
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
5C:
embryonic day 8.5
(more )
Specimen
5C:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: neural ectoderm |
Present |
Regionally restricted |
5C
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Expression in most anterior neurectoderm.
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Specimen
5D:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Mutant Allele(s):
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Otx2tm1Sia/Otx2tm4Sia
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: neural ectoderm |
Present |
Regionally restricted |
5D
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Expression domain in most anterior neurectoderm is significantly reduced compared with wild type.
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Specimen
6O:
embryonic day 7.8
(more )
Specimen
6O:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 7.8
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: neural ectoderm |
Present |
Regionally restricted |
6O
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Expression in anterior neural ridge.
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Specimen
6P:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Mutant Allele(s):
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Otx2tm1Sia/Otx2tm4Sia
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Age:
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embryonic day 7.8
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: neural ectoderm |
Present |
Regionally restricted |
6P
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Expression in anterior neural ridge unchanged compared with wild type.
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Analysis Tools