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Gene Expression Data
Assay Details
Assay
Reference: J:73072 Bhushan A, et al., Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development. 2001 Dec;128(24):5109-17
Assay type: RNA in situ
MGI Accession ID: MGI:2178941
Gene symbol: Fgf10
Gene name: fibroblast growth factor 10
Probe: Fgf10 probe4
Probe preparation: Antisense RNA
Results
Specimen 1A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Present 1A Expression is present in two thin stripes in the mesenchyme in the posterior foregut where the dorsal and ventral pancreatic buds will emerge.
TS15: lung mesenchyme Present Regionally restricted 1A Expression is present in the mesenchyme surrounding the forming lung buds.
Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS18: foregut-midgut junction mesenchyme Present Regionally restricted 1B Expression is present in the mesenchyme surrounding the prospective pancreas.
TS18: stomach mesenchyme Present Regionally restricted 1B Expression is present in the mesenchyme surrounding the posterior/caudal region of the stomach.
TS18: duodenum rostral part mesenchyme Absent 1B There is no expression in the mesenchyme surrounding the rostral duodenum.
Specimen 1C: embryonic day 10.5 (more )
Note: This is a 20 micron vibratome section from the embryo pictured in 1B.
Structure Level Pattern Image Note
TS18: foregut-midgut junction mesenchyme Present Regionally restricted 1C Expression is present in the mesenchyme adjacent to the dorsal pancreatic bud.
Specimen 1D: embryonic day 10.5 (more )
Note: This is a 20 micron vibratome section from the embryo pictured in 1B.
Structure Level Pattern Image Note
TS18: foregut-midgut junction mesenchyme Present Regionally restricted 1D Expression is present in the mesenchyme adjacent to the prospective ventral pancreatic bud.
Specimen 1E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: foregut-midgut junction mesenchyme Strong Regionally restricted 1E Expression is present at high levels in the mesenchyme surrounding the dorsal pancreatic bud; it is only present at low levels around the ventral bud. (There is also weak, non-specific staining observed in the stomach due to the trapping of the probe.)
Specimen Not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: foregut-midgut junction mesenchyme Absent There is virtually no expression in the mesenchyme surrounding either pancreatic bud.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory