Col10a1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:73071 Long F, et al., Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development. 2001 Dec;128(24):5099-108
Assay type:	RNA in situ
MGI Accession ID:	MGI:2178830
Gene symbol:	Col10a1
Gene name:	collagen, type X, alpha 1

Probe:	Col10a1 probe1
Probe preparation:	Antisense labelled with S35 RNA

Results

Specimen 5 Col10a1 E14.5 WT: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: tibia cartilage condensation	Present		5_Col10a1 WT E14.5	Expression was present in the chondrocytes.

Specimen 5 Col10a1 E14.5 Cre10;Smo^n/c: embryonic day 14.5; Smo^tm1Amc/Smo^tm2Amc, Tg(Col2a1-cre)10Amc/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: tibia cartilage condensation	Present	Regionally restricted	5_Col10a1 Cre10;Smo^n/c E14.5	Expression was present in chondrocytes.

Specimen 5 Col10a1 E14.5 Ihh^n/n: embryonic day 14.5; Ihh^tm1Amc/Ihh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS22: tibia cartilage condensation	Weak		5_Col10a1 Ihh^n/n E14.5	Expression was present in the chondrocytes at lower level than in wild-type embryos.

Specimen 5 Col10a1 E18.5 WT: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: tibia	Present		5_Col10a1 WT E18.5	Expression was present in the chondrocytes.

Specimen 5 Col10a1 E18.5 Cre10;Smo^n/c: embryonic day 18.5; Smo^tm1Amc/Smo^tm2Amc, Tg(Col2a1-cre)10Amc/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: tibia	Present	Regionally restricted	5_Col10a1 Cre10;Smo^n/c E18.5	Expression was maintained along the longitudinal axis of the tibia similar to the wild type.

Specimen 5 Col10a1 E18.5 Ihh^n/n: embryonic day 18.5; Ihh^tm1Amc/Ihh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS26: tibia	Present		5_Col10a1 Ihh^n/n E18.5	Expression was present in the bulk of the cartilage.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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