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Gene Expression Data
Assay Details
Assay
Reference: J:74784 Adams IR, et al., Sexually dimorphic development of mouse primordial germ cells: switching from oogenesis to spermatogenesis. Development. 2002 Mar;129(5):1155-64
Assay type: RNA in situ
MGI Accession ID: MGI:2178296
Gene symbol: Ptgds
Gene name: prostaglandin D2 synthase (brain)
Probe: Ptgds cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3A left: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: urogenital ridge Absent 3A left

Specimen 3A right: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: urogenital ridge Absent 3A right

Specimen 3B: embryonic day 11.5 (more )
Note: This specimen was collected later in the day than those pictured in 3A.
Structure Level Pattern Image Note
TS19: gonad Present 3B There was some expression present in the forming testis cords.

Specimen 3C left: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ovary Absent 3C left Expression is absent in the urogenital ridge.

Specimen 3C right: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: Sertoli cell Sertoli cell Strong 3C right
TS20: germ cell of testis Strong 3C right

Specimen 3D left: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: ovary Absent 3D left Expression is absent in the urogenital ridge.

Specimen 3D right: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: Sertoli cell Sertoli cell Strong 3D right
TS21: germ cell of testis Strong 3D right

Specimen 3E: embryonic day 14.5; KitW-e/KitW-e (more )
Structure Cell Type Level Pattern Image Note
TS22: testis Present 3E There is staining in the testis cords and, presumably, in the prospective Sertoli cells.
TS22: Sertoli cell Sertoli cell Present 3E
TS22: germ cell of testis Absent 3E Expression is lacking from the germ cells because there are no primordial germ cells in these mutants.

Specimen 3F: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: germ cell of testis Present 3F
TS21: Sertoli cell Sertoli cell Present 3F Expression is present in the prospective Sertoli cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory