Gene Expression Data
Assay Details
Assay
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Reference:
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J:73069
Wang W, et al., Hmx2 homeobox gene control of murine vestibular morphogenesis. Development. 2001 Dec;128(24):5017-29
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2155143
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Gene symbol:
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Bmp4
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Gene name:
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bone morphogenetic protein 4
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Probe:
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Bmp4 probe12
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
7P:
embryonic day 11.5
(more )
Specimen
7P:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS19: inner ear |
Present |
Regionally restricted |
7O/P
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Expression is present in discrete spots in the lateral aspect of the otic epithelium, in the presumptive anterior and lateral cristae, and in a patch in the posterior otic vesicle. There is no expression in the presumptive fusion plate.
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Specimen
7R:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2tm1Tlu
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS19: inner ear |
Present |
Regionally restricted |
7Q/R
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There is ectopic expression in the lateral aspect of the otic epithelium, including the presumptive fusion plate; expression there is homogeneous, rather than present in discrete spots as in wild-type embryos.
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Specimen
7T:
embryonic day 12.0
(more )
Specimen
7T:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: inner ear |
Present |
Regionally restricted |
7S/T
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Expression is present in discrete regions in the lateral portion of the otic vesicle. It is absent in the fusion plate.
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Specimen
7V:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2tm1Tlu
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: inner ear |
Present |
Regionally restricted |
7U/V
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There is homogeneous expression in the lateral portion of the otic vesicle. This is due to ectopic expression in the fusion plate; this expression is absent in wild-type embryos.
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