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Gene Expression Data
Assay Details
Assay
Reference: J:71995 Kinder SJ, et al., The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm. Development. 2001 Sep;128(18):3623-34
Assay type: RNA in situ
MGI Accession ID: MGI:2154955
Gene symbol: Foxa2
Gene name: forkhead box A2
Probe: Hnf3b cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A, ES: embryonic day 6.5 (more )
Note: Early streak stage.
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 1A ES
TS9: embryo Present Regionally restricted 1A ES Expression is detected in the epiblast distal to the newly formed primitive streak and in the posterior germ layer at the location of the early-gastrul organizer.

Specimen 1A, MS: embryonic day 7.0 (more )
Note: Embryo is at the mid-streak stage.
Structure Level Pattern Image Note
TS10: primitive streak Present Regionally restricted 1A MS Expression is detected at the anterior end of the elongating primitive streak.

Specimen 1A, LS: embryonic day 7.0 (more )
Note: Embryo is at the late streak stage.
Structure Level Pattern Image Note
TS10: embryo ectoderm Present Regionally restricted 1A LS Expression is detected in the prospective foregut endoderm, the axial mesoderm, the mesoderm and ectoderm of the prospective cranial region and is shifted distally with the extension of the primitive streak.
TS10: embryo endoderm Present Regionally restricted 1A LS Expression is detected in the prospective foregut endoderm, the axial mesoderm, the mesoderm and ectoderm of the prospective cranial region and is shifted distally with the extension of the primitive streak.
TS10: embryo mesoderm Present Regionally restricted 1A LS Expression is detected in the prospective foregut endoderm, the axial mesoderm, the mesoderm and ectoderm of the prospective cranial region and is shifted distally with the extension of the primitive streak.
TS10: primitive streak Present Regionally restricted 1A LS Expression is detected in the prospective foregut endoderm, the axial mesoderm, the mesoderm and ectoderm of the prospective cranial region and is shifted distally with the extension of the primitive streak.

Specimen 1A, EB: embryonic day 7.5 (more )
Note: Embryo is at the early bud stage.
Structure Level Pattern Image Note
TS10: node Present 1A EB
TS10: embryo endoderm Present Regionally restricted 1A EB Expression is detected in the prospective foregut endoderm.
TS10: embryo mesoderm Present Regionally restricted 1A EB Expression is detected in the axial mesoderm and the mesoderm of the prospective cranial region.
TS10: embryo ectoderm Present Regionally restricted 1A EB Expression is detected in the ectoderm of the prospective cranial region.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory