Gene Expression Data
Assay Details
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Assay
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Reference:
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J:72724
Toresson H, et al., A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice. Development. 2001 Dec;128(23):4769-80
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:2154696
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Gene symbol:
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Isl1
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Gene name:
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ISL1 transcription factor, LIM/homeodomain
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Antibody:
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Anti-Isl1
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
1A:
embryonic day 18.5
(more )
Specimen
1A:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
1B:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Gsx2tm1Ssp/Gsx2tm1Ssp
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: telencephalon |
Present |
Uniform |
1B
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The reduced area of expression is due to a 55% reduction in the volume of the striatal complex.
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Specimen
5A:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Gsx1tm1Ssp/Gsx1tm1Ssp
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: telencephalon |
Present |
Uniform |
5A
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Expression in this mutant is the same as in wild-type embryos.
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Specimen
5B:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * 129S2/SvPas
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Mutant Allele(s):
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Gsx1tm1Ssp/Gsx1tm1Ssp Gsx2tm1Ssp/Gsx2tm1Ssp
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: telencephalon |
Present |
Uniform |
5B
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The striatum in this mutant is only rudimentary.
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