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Gene Expression Data
Assay Details
Assay
Reference: J:72302 Caric D, et al., EGFRs mediate chemotactic migration in the developing telencephalon. Development. 2001 Nov;128(21):4203-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2152411
Gene symbol: Egfr
Gene name: epidermal growth factor receptor
Antibody: anti-EGFR
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3A: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: telencephalon Present 3A Relatively low staining.

Specimen 3B: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Present Graded 3B Greater expression in lateral (L) than medial (M) regions.
TS24: cerebral cortex intermediate zone Strong 3B High levels in radial migration pathway from proliferative zone to cortical plate via intermediate zone.

Specimen 3C: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 3C Concentrated at the apical surfaces of cells lining the lateral ventricle.

Specimen 3D: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: telencephalon Present Uniform 3D Distributed uniformly over cell surfaces.

Specimen 3G: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: telencephalon Strong Regionally restricted 3G High levels in migration pathways, including at beginning of lateral cortical stream, as pathway curves around lateral ganglionic eminence (LGE).

Specimen 3H: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: telencephalon Strong Regionally restricted 3H High levels in migration pathways, including lateral cortical stream (LCS) in ventrolateral cortex; expression in cells leaving to migrate radially to cortical plate.

Specimen 3I: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: telencephalon Strong Regionally restricted 3I High levels in migration pathways, including lateral cortical stream leading into piriform cortex (P).

Specimen 3J: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: rostral migratory stream Strong Regionally restricted 3J High levels in migration pathways, including in rostral migratory stream (RMS) from anterior subventricular zone to olfactory bulb.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory