Gene Expression Data
Assay Details
Assay
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Reference:
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J:71034
Boyl PP, et al., Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR. Development. 2001 Aug;128(15):2989-3000
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2150147
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Gene symbol:
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Otx2
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Gene name:
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orthodenticle homeobox 2
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Results
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Specimen
3A wt:
embryonic day 6.5
(more )
Specimen
3A wt:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 6.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
3B Otx2 +/-:
embryonic day 6.5; Otx2tm1Pas/Otx2 +
(more )
Specimen
3B Otx2 +/-:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm1Pas/Otx2+
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Age:
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embryonic day 6.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
3C Otx2 l/l:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm1Pas/Otx2tm2Asim
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Age:
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embryonic day 6.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
3D Otx2 l/-:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm2Asim/Otx2tm2Asim
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Age:
|
embryonic day 6.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
3E wt:
embryonic day 7.75
(more )
Specimen
3E wt:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 7.75
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
3F Otx2 +/-:
embryonic day 7.75; Otx2tm1Pas/Otx2 +
(more )
Specimen
3F Otx2 +/-:
(close )
Genetic Background:
|
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm1Pas/Otx2+
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Age:
|
embryonic day 7.75
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
3G Otx2 l/l:
(close )
Genetic Background:
|
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm1Pas/Otx2tm2Asim
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Age:
|
embryonic day 7.75
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
3H Otx2 l/-:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm2Asim/Otx2tm2Asim
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Age:
|
embryonic day 7.75
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
6A wt:
embryonic day 6.5
(more )
Specimen
6A wt:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 6.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
6B Otx2 l/-:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm1Pas/Otx2tm2Asim
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Age:
|
embryonic day 6.5
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
Not shown Otx2 l/l:
(close )
Genetic Background:
|
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm2Asim/Otx2tm2Asim
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Age:
|
embryonic day 6.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
6G wt:
embryonic day 7.5
(more )
Specimen
6G wt:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 7.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
6H Otx2 l/-:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm1Pas/Otx2tm2Asim
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Age:
|
embryonic day 7.5
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS11: neural ectoderm |
Present |
Regionally restricted |
6H
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Expression is anterior. Expression in the mutant is similar to that seen in wild type.
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TS11: mesendoderm |
Present |
Regionally restricted |
6H
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Expression is in the axial mesendoderm. Expression in the mutant is similar to that seen in wild type.
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TS11: extraembryonic visceral endoderm |
Present |
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6H
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Expression in the mutant is similar to that seen in wild type.
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Specimen
Not shown Otx2 l/l:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
|
Otx2tm2Asim/Otx2tm2Asim
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Age:
|
embryonic day 7.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS11: neural ectoderm |
Present |
Regionally restricted |
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Expression is anterior. Expression in the mutant is similar to that seen in wild type.
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TS11: mesendoderm |
Present |
Regionally restricted |
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Expression is present in the axial mesendoderm. Expression in the mutant is similar to that seen in wild type.
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TS11: extraembryonic visceral endoderm |
Present |
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Expression in the mutant is similar to that seen in wild type.
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Specimen
8A wt:
embryonic day 10.5
(more )
Specimen
8A wt:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
8B Otx2 l/l:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm2Asim/Otx2tm2Asim
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Age:
|
embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS17: brain |
Present |
Regionally restricted |
8B
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Expression is present in a smaller domain in the mutant than in wild type.
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Specimen
8C Otx2 l/-:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm1Pas/Otx2tm2Asim
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Age:
|
embryonic day 10.5
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS17: brain |
Present |
Regionally restricted |
8C
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Expression is present in the rostral-most neuroectoderm.
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