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Gene Expression Data
Assay Details
Assay
Reference: J:62941 Malpel S, et al., Regulation of retinoic acid signaling during lung morphogenesis. Development. 2000 Jul;127(14):3057-67
Assay type: RNA in situ
MGI Accession ID: MGI:2150103
Gene symbol: Cyp26a1
Gene name: cytochrome P450, family 26, subfamily a, polypeptide 1
Probe: P450RAI cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: lung Absent 5A
TS15: respiratory tract Absent 5A
Specimen 5B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: left lung rudiment epithelium Weak Uniform 5B
TS17: right lung rudiment epithelium Weak Uniform 5B
TS17: trachea Absent 5B
TS17: alimentary system Absent 5B
Specimen 5C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: left lung rudiment epithelium Present Graded 5C Proximal-distal gradient in lung epithelium; higher levels in distal buds.
TS19: right lung rudiment epithelium Present Graded 5C Proximal-distal gradient in lung epithelium; higher levels in distal buds.
Specimen 5D: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: left lung epithelium Present Graded 5D Proximal-distal gradient in lung epithelium; higher levels in distal buds.
TS21: right lung epithelium Present Graded 5D Proximal-distal gradient in lung epithelium; higher levels in distal buds.
Specimen 5E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: trachea epithelium Present 5E left , 5E right
TS22: trachea mesenchyme Present Regionally restricted 5E right , 5E left In trachea and main bronchi, mesenchymal expression appears to delineate prospective tracheal rings.
TS22: main bronchus mesenchyme Present Regionally restricted 5E right , 5E left In trachea and main bronchi, mesenchymal expression appears to delineate prospective tracheal rings.
TS22: left lung epithelium Present Regionally restricted 5E right , 5E left Proximal-distal gradient in lung epithelium; higher levels in distal buds.
TS22: right lung epithelium Present Regionally restricted 5E right , 5E left Proximal-distal gradient in lung epithelium; higher levels in distal buds.
TS22: left lung mesenchyme Weak Regionally restricted 5E left , 5E right Weak signals in lung mesenchyme between distal buds.
TS22: right lung mesenchyme Weak Regionally restricted 5E left , 5E right Weak signals in lung mesenchyme between distal buds.
Specimen 5F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: respiratory system Present Regionally restricted 5F Expression has shifted from distal to proximal sites.
TS24: trachea Present 5F Restricted to main bronchi and trachea.
TS24: main bronchus Present 5F Restricted to main bronchi and trachea.
TS24: left lung Weak Regionally restricted 5F Hardly detected in distal lung.
TS24: right lung Weak Regionally restricted 5F Hardly detected in distal lung.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory