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Gene Expression Data
Assay Details
Assay
Reference: J:32953 Fitzpatrick DR, et al., Differential expression of TGF beta isoforms in murine palatogenesis. Development. 1990 Jul;109(3):585-95
Assay type: RNA in situ
MGI Accession ID: MGI:2136297
Gene symbol: Tgfb1
Gene name: transforming growth factor, beta 1
Probe: Tgfb1 probe2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen not shown: embryonic day 11.5 (more )
Note: very early palatal shelves
Structure Level Pattern Image Note
TS19: palatal shelf Absent
Specimen not shown: embryonic day 12.5 (more )
Note: very early palatal shelves
Structure Level Pattern Image Note
TS20: palatal shelf Absent
Specimen 1C: embryonic day 13.5 (more )
Note: late vertical palatal shelves
Structure Level Pattern Image Note
TS21: palatal shelf Absent 1C Palatal shelves show no specific hybridization; no hybridization in epithelial cells within hyperplastic nodules in medial edge epithelia.
TS21: submandibular gland primordium Strong 1C Strong hybridisation to the submandibular gland.
Specimen 2A,2B: embryonic day 14.0 (more )
Note: horizontal palatal shelves
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present Regionally restricted 2B , 2A Expression in medial edge epithelium.
TS22: maxilla Present Regionally restricted 2B , 2A Expression in regions of membranous ossification within the developing maxilla.
Specimen 2C,2D: embryonic day 14.0 (more )
Note: horizontal palatal shelves
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present Regionally restricted 2D , 2C Expression in medial edge epithelium.
Specimen 3B: embryonic day 14.5 (more )
Note: fusing palate
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present Regionally restricted 3B Medial edge epithelia fuse to form the epithelial seam; faint hybridization localised to epithelial cells of the seam.
Specimen 4B: embryonic day 15.5 (more )
Note: maturing palate
Structure Level Pattern Image Note
TS23: nose Present Regionally restricted 4B Expression is limited to areas of ossification within the palate and around the nasal processes.
TS23: palatal shelf mesenchyme Present Regionally restricted 4B Expression is limited to areas of ossification within the palate and around the nasal processes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory