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Gene Expression Data
Assay Details
Assay
Reference: J:3685 Shimamura K, et al., Local and transient expression of E-cadherin involved in mouse embryonic brain morphogenesis. Development. 1992 Dec;116(4):1011-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2135569
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-E-cadherin
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 2A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future brain Strong Regionally restricted 2A Expression is detected in the head region with faint expression in the neural plate and strong expression in the overlying ectoderm.
Specimen 2B: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 2B Authors state that expression is detected in restricted regions of the diencephalon (hypothalamus) and the neural tube.
TS20: hypothalamus Present Regionally restricted 2B Authors state that expression is detected in restricted regions of the diencephalon (hypothalamus) and the neural tube.
Specimen 2C: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: midbrain lateral wall Present Regionally restricted 2C Expression is detected in radially arranged clusters in the neuroepithelial layer of the lateral midbrain. Hiigher staining ventrally.
Specimen 2D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 2D Expression is detected at the diencephalon/mesencephalon border and is restricted to the ventricular zone.
TS20: midbrain ventricular layer Present Regionally restricted 2D Expression is detected at the diencephalon/mesencephalon border and is restricted to the ventricular zone.
Specimen 3A/B: embryonic day 12.5 (more )
Note: Pane B is a phase contrast of A.
Structure Level Pattern Image Note
TS20: cerebellum primordium Present 3A/B
Specimen 3C/D/E: embryonic day 12.5 (more )
Note: Pane E is a phase contrast of C and D is a high magnification of C.
Structure Level Pattern Image Note
TS20: metencephalon Present Regionally restricted 3C , 3D/E Cdh1 positive fibers extend to the marginal zone and migrated upwards to the ventral midline.
Specimen 3F/G: embryonic day 13.5 (more )
Note: Pane G is a phase contrast of F.
Structure Level Pattern Image Note
TS21: midbrain roof plate Present Regionally restricted 3F/G Two Cdh1 positive columns of expression are detected in the mesencephalic roof plate.
Specimen 7B: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: brain Present 7B
Specimen Not shown: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: future brain Trace
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory