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Gene Expression Data
Assay Details
Assay
Reference: J:21617 Gunther T, et al., Open brain, a new mouse mutant with severe neural tube defects, shows altered gene expression patterns in the developing spinal cord. Development. 1994 Nov;120(11):3119-30
Assay type: RNA in situ
MGI Accession ID: MGI:1933419
Gene symbol: Foxa2
Gene name: forkhead box A2
Probe: c21
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 6C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord floor plate Present 6C

Specimen 6D: embryonic day 12.5; Rab23opb/Rab23opb (more )
Note: The original opb carriers were of a mixed outbred NMRI background. The opb mutant embryos used in this study were derived subsequent to at least 6 crosses of opb mutant males to wild-type C57Bl/6 females.
Structure Level Pattern Image Note
TS20: spinal cord floor plate Present 6D The area of Foxa2-expressing cells was extended compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/30/2025
MGI 6.24
The Jackson Laboratory