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Gene Expression Data
Assay Details
Assay
Reference: J:45302 Erickson SL, et al., ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice. Development. 1997 Dec;124(24):4999-5011
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1929653
Gene symbol: En1
Gene name: engrailed 1
Antibody: alpha Enhb-1
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: Antibody detects both En1 and En2 gene products.
Results
Specimen 5A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 5A Engrailed expression is present in (not restricted to) the isthmic and cerebellar neuroepithelia.
TS17: midbrain-hindbrain junction Present Regionally restricted 5A Engrailed expression is present in (not restricted to) the isthmic and cerebellar neuroepithelia.
Specimen 5B: embryonic day 10.5; Nrg1tm1Gne/Nrg1tm1Gne (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 5B Engrailed expression present in isthmic neuroepithelium with no expression in the cerebellum.
TS17: midbrain-hindbrain junction Present Regionally restricted 5B Engrailed expression present in isthmic neuroepithelium with no expression in the cerebellum.
Specimen 5C: embryonic day 10.5; Erbb2tm1Gne/Erbb2tm1Gne (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Diffuse 5C Very slight diffuse engrailed expression in isthmic and cerebellar neuroepithelia.
TS17: midbrain-hindbrain junction Present Diffuse 5C Very slight diffuse engrailed expression in isthmic and cerebellar neuroepithelia.
Specimen 5D: embryonic day 10.5; Erbb3tm1Gne/Erbb3tm1Gne (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 5D Engrailed expression present in isthmic neuroepithelium with no expression in the cerebellum.
TS17: midbrain-hindbrain junction Present Regionally restricted 5D Engrailed expression present in isthmic neuroepithelium with no expression in the cerebellum.
Specimen 5F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cerebellum primordium Present Regionally restricted 5F Engrailed expression present in (not restricted to) the isthmic and cerebellar neuroepithelia.
TS19: midbrain-hindbrain junction Present Regionally restricted 5F Engrailed expression present in (not restricted to) the isthmic and cerebellar neuroepithelia.
Specimen 5H: embryonic day 11.5; Erbb3tm1Gne/Erbb3tm1Gne (more )
Structure Level Pattern Image Note
TS19: midbrain-hindbrain junction Present Regionally restricted 5H
TS19: cerebellum primordium Absent 5H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory