About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:66592 Liu A, et al., EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region. Development. 2001 Jan;128(2):181-91
Assay type: RNA in situ
MGI Accession ID: MGI:1929104
Gene symbol: Gbx2
Gene name: gastrulation brain homeobox 2
Probe: Gbx2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen E. 9.5: embryonic day 9.5; En1tm1Alj/En1+, En2tm1Alj/En2tm1Alj (more )
Structure Level Pattern Image Note
TS15: embryo Present
Specimen E. 9.5': embryonic day 9.5; En1tm2Alj/En1tm2Alj, En2tm2Alj/En2tm2Alj (more )
Structure Level Pattern Image Note
TS15: embryo Absent
Specimen 3. B: embryonic day 8.0; En1tm1Alj/En1+, En2tm1Alj/En2tm1Alj (more )
Note: Embryo is at the 7 somite stage.
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted 3B Expression is detected in the mesencephalon and metencephalon.
TS12: future midbrain Present Regionally restricted 3B Expression is detected in the mesencephalon and metencephalon.
Specimen 3. B': embryonic day 8.0; En1tm2Alj/En1tm2Alj, En2tm2Alj/En2tm2Alj (more )
Note: Embryo is at the 7 somite stage.
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted 3B'
TS12: future midbrain Present Regionally restricted 3B'
Specimen 3. G: embryonic day 8.5; En1tm1Alj/En1+, En2tm1Alj/En2tm1Alj (more )
Note: Embryo is at the 11 somite stage.
Structure Level Pattern Image Note
TS13: future hindbrain Present Regionally restricted 3G Expression is detected in the anterior hindbrain
Specimen 3. G': embryonic day 8.5; En1tm2Alj/En1tm2Alj, En2tm2Alj/En2tm2Alj (more )
Note: Embryo is at the 11 somite stage.
Structure Level Pattern Image Note
TS13: future hindbrain Present Regionally restricted 3G' Expression is detected in the anterior hindbrain but is down regulated compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory