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Gene Expression Data
Assay Details
Assay
Reference: J:24115 Shawlot W, et al., Requirement for Lim1 in head-organizer function [see comments]. Nature. 1995 Mar 30;374(6521):425-30
Assay type: RNA in situ
MGI Accession ID: MGI:1926826
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Probe: Otx2 cDNA12
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Wild-type specimens were either homozygous wild-type or heterozygous mutant.
Results
Specimen not shown: embryonic day 7.5; Lhx1tm1Bhr/Lhx1tm1Bhr (more )
Note: Head-fold stage.
Structure Level Pattern Image Note
TS11: embryo Absent

Specimen 4a: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future midbrain Present 4a Expression in the forebrain and midbrain.
TS13: future prosencephalon Present 4a Expression in the forebrain and midbrain.

Specimen 4b: embryonic day 8.5; Lhx1tm1Bhr/Lhx1tm1Bhr (more )
Structure Level Pattern Image Note
TS13: future midbrain Absent 4b
TS13: future prosencephalon Absent 4b


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory