About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:60837 Zhang Y, et al., A new function of BMP4: dual role for BMP4 in regulation of Sonic hedgehog expression in the mouse tooth germ. Development. 2000 Apr;127(7):1431-43
Assay type: RNA in situ
MGI Accession ID: MGI:1355022
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA10
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1. A.: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mandible primordium Present Regionally restricted 1A Expression is detected in the dental epithelium of the incisor and molar tooth germs.
TS19: maxilla primordium Present Regionally restricted 1A Expression is detected in the dental epithelium of the incisor and molar tooth germs.
Specimen 1. B.: embryonic day 11.5; Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS19: mandible primordium Present Regionally restricted 1B Expression is detected in the dental epithelium of the incisor and molar tooth germs.
TS19: maxilla primordium Present Regionally restricted 1B Expression is detected in the dental epithelium of the incisor and molar tooth germs.
Specimen 1. C.: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mandible primordium Present Regionally restricted 1C Expression is detected in the dental epithelium of the incisor and molar tooth germs.
TS20: maxillary process epithelium Present Regionally restricted 1C Expression is detected in the dental epithelium of the incisor and molar tooth germs.
Specimen 1. D.: embryonic day 12.5; Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS20: mandible primordium Weak Regionally restricted 1D Expression is detected in the dental epithelium of the incisor tooth germ but is absent in the molar epithelium.
TS20: maxillary process epithelium Weak Regionally restricted 1D Expression is detected in the dental epithelium of the incisor tooth germ but is absent in the molar epithelium.
Specimen 1. E.: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw incisor Strong 1E
TS21: lower jaw molar Strong 1E
TS21: upper jaw incisor Strong 1E
TS21: upper jaw molar Strong 1E
TS21: tongue Present 1E
Specimen 1. F.: embryonic day 13.5; Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS21: lower jaw incisor Absent 1F
TS21: lower jaw molar Absent 1F
TS21: upper jaw incisor Absent 1F
TS21: upper jaw molar Absent 1F
TS21: tongue Present 1F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory