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Gene Expression Data
Assay Details
Assay
Reference: J:60986 Park HL, et al., Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development. 2000 Apr;127(8):1593-605
Assay type: RNA in situ
MGI Accession ID: MGI:1354543
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Probe: Nkx2.1 probe8
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5A: embryonic day 11.5-12.5 (more )
Structure Level Pattern Image Note
TS20: corpus striatum Present Regionally restricted 5A Expression was detected in the midline of the striatum.
TS20: medial ganglionic eminence Present 5A
Specimen 5B: embryonic day 11.5-12.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS20: corpus striatum Present Regionally restricted 5B Expression was detected in the midline of the striatum as in wild type.
TS20: medial ganglionic eminence Present 5B Expressed as in wild type.
Specimen 5C: embryonic day 11.5-12.5; Gli1tm1Alj/Gli1tm1Alj, Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS20: corpus striatum Present Regionally restricted 5C Expression was detected in the midline of the striatum as in wild type.
TS20: medial ganglionic eminence Present 5C Expressed as in wild type.
Specimen 5D: embryonic day 11.5-12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 5D Expression was detected in the ventral midline of rostral diencephalon.
Specimen 5E: embryonic day 11.5-12.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 5E Expression was detected in the ventral midline of rostral diencephalon as in wild type, although in some embryos there may be a ventral shift in the expression domain.
Specimen 5F: embryonic day 11.5-12.5; Gli1tm1Alj/Gli1tm1Alj, Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS20: diencephalon Absent 5F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory