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Gene Expression Data
Assay Details
Assay
Reference: J:60986 Park HL, et al., Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development. 2000 Apr;127(8):1593-605
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1354541
Gene symbol: Nkx2-2
Gene name: NK2 homeobox 2
Antibody: anti Nkx2.2
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 4D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Present Regionally restricted 4D Expression is in ventral intermediate neurons between Isl1/2-expressing cells and the floorplate.
Specimen 4E: embryonic day 10.5; Gli1tm1Alj/Gli1tm1Alj, Gli2tm1Alj/Gli2+ (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Weak Regionally restricted 4E Expression is closer to the midline than it is in wild-type embryos.
Specimen 4F: embryonic day 10.5; Gli1tm1Alj/Gli1tm1Alj, Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Absent 4F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory