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Gene Expression Data
Assay Details
Assay
Reference: J:60986 Park HL, et al., Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development. 2000 Apr;127(8):1593-605
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1354539
Gene symbol: Isl2
Gene name: insulin related protein 2 (islet 2)
Antibody: anti-C-Isl-1 protein (K5)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Present Regionally restricted 4A Expression is in the motoneurons lateral to the floorplate.

Specimen 4B: embryonic day 10.5; Gli1tm1Alj/Gli1tm1Alj, Gli2tm1Alj/Gli2+ (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Present Regionally restricted 4B Expression in some embryos is in the floorplate region in patches along the length of the spinal cord.

Specimen 4C: embryonic day 10.5; Gli1tm1Alj/Gli1tm1Alj, Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Present Regionally restricted 4C Expression is in patches of cells in the floorplate.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory