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Gene Expression Data
Assay Details
Assay
Reference: J:59281 Manaia A, et al., Lmo2 and GATA-3 associated expression in intraembryonic hemogenic sites. Development. 2000 Feb;127(3):643-53
Assay type: RNA in situ
MGI Accession ID: MGI:1352410
Gene symbol: Lmo2
Gene name: LIM domain only 2
Probe: Lmo2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A top panel: embryonic day 8.0 (more )
Note: Neural-plate stage
Structure Level Pattern Image Note
TS11: extraembryonic component Present Regionally restricted 1A top Expression delineates a ring in the extraembryonic mesoderm.
Specimen 1B top panel: embryonic day 8.0 (more )
Note: Neural-plate stage
Structure Level Pattern Image Note
TS11: blood island Present Regionally restricted 1B top In a slightly later stage than (A), expression begins to form patches in immature blood islands.
TS11: extraembryonic component Present Regionally restricted 1B top In a slightly later stage than (A), expression begins to form patches in immature blood islands.
Specimen 1C top panel: embryonic day 8.0 (more )
Note: Neural-plate stage
Structure Level Pattern Image Note
TS11: blood island Present Regionally restricted 1C top As blood island development progresses, a ring of expression is forme
Specimen 1A bottom panel: embryonic day 8.0 (more )
Note: Neural-plate stage
Structure Level Pattern Image Note
TS11: extraembryonic component Present Regionally restricted 1A bottom Expression is in the extraembryonic mesoderm.
Specimen 1B bottom panel: embryonic day 8.0 (more )
Note: Neural-plate stage
Structure Level Pattern Image Note
TS11: blood island Present Regionally restricted 1B bottom In a later stage than (A) expression is in immature blood islands.
TS11: extraembryonic component Present Regionally restricted 1B bottom In a later stage than (A) expression is in immature blood islands.
Specimen 1C bottom panel: embryonic day 8.0 (more )
Note: Neural-plate stage
Structure Level Pattern Image Note
TS11: blood island Present Regionally restricted 1C bottom The expression forms a rin
Specimen 1D top panel: embryonic day 8.0 (more )
Note: Late head-fold stage.
Structure Level Pattern Image Note
TS11: allantois Present 1D top
TS11: blood island Present 1D top
TS11: head mesenchyme Present 1D top
TS11: embryo Present 1D top Expression is in cells at the boudary of the intraembryonic and extraembryonic junction.
Specimen 1D bottom panel: embryonic day 8.0 (more )
Note: Late head-fold stage.
Structure Level Pattern Image Note
TS11: allantois Present 1D bottom
TS11: blood island Present 1D bottom
TS11: head mesenchyme Present 1D bottom
TS11: embryo Present 1D bottom Expression is at the border of the intraembryonic and extraembryonic junction.
Specimen 1F: embryonic day 8.0 (more )
Note: Late head-fold stage.
Structure Level Pattern Image Note
TS11: blood island Strong 1F
TS11: allantois Present Regionally restricted 1F Expression is in the caudal splanchnopleure and in the angioblasts of the allantois.
TS11: embryo mesenchyme Present Regionally restricted 1F Expression is in the caudal splanchnopleure and in the angioblasts of the allantois.
Specimen 1G: embryonic day 8.5 (more )
Note: 15-somite stage.
Structure Level Pattern Image Note
TS13: branchial arch Present 1G
TS13: arterial system Present Regionally restricted 1G In the paired aorta, expression is high caudally and appears in the trunk.
TS13: embryo Strong Regionally restricted 1G The posterior ventral mesoderm is strongly stained.
TS13: extraembryonic component Weak Regionally restricted 1G The expression in the yolk sac is decreased compared to earlier stages.
Specimen 1H: embryonic day 9.5 (more )
Note: 20-25 somite stage.
Structure Level Pattern Image Note
TS14: branchial arch Present 1H
TS14: trunk mesenchyme Present Regionally restricted 1H Expression is in the posterior ventral mesoderm.
TS14: cardiovascular system Present Regionally restricted 1H Expression is in cranial capillaries and intersomitic vessels.
TS14: dorsal aorta Present Regionally restricted 1H Expression is in the truncal aorta.
TS14: extraembryonic component Weak Regionally restricted 1H Expression is downregulated in circulating hematopoetic cells.
Specimen 2A: embryonic day 8.0 (more )
Note: 5-somite stage. This embryo is ventral-side up and the yolk sac has been removed.
Structure Level Pattern Image Note
TS12: somite 01 Present 2A
TS12: somite 02 Present 2A
TS12: somite 03 Present 2A
TS12: allantois Present Regionally restricted 2A Expression is in the vasculature.
TS12: cardiovascular system Present Regionally restricted 2A Expression is in the vasculature of the splanchnopleura.
TS12: splanchnopleure Present Regionally restricted 2A Expression is in the vasculature of the splanchnopleura.
Specimen 2B: embryonic day 8.0 (more )
Note: 5-somite stage. The plane of this section is shown in panel A.
Structure Level Pattern Image Note
TS12: head somite Present 2B
TS12: somatopleure Present 2B
TS12: embryo endoderm Absent 2B
Specimen 2C: embryonic day 8.0 (more )
Note: 5-somite stage embryo. The plane of this section is shown in panel A.
Structure Level Pattern Image Note
TS12: embryo endoderm Absent 2C
TS12: dorsal aorta Present Regionally restricted 2C Expression is in the endothelial cells.
TS12: embryo mesenchyme Present 2C
Specimen 2D: embryonic day 8.0 (more )
Note: 5-somite stage. The plane of this section is shown in panel A.
Structure Level Pattern Image Note
TS12: embryo mesenchyme Present Regionally restricted 2D Expression is in caudal mesoderm.
TS12: dorsal aorta Present Regionally restricted 2D Expression is in endothelial cells.
TS12: yolk sac Absent 2D There is no expression in endothelial cells.
TS12: splanchnopleure Present Regionally restricted 2D Expression is in the caudal endoderm.
Specimen 3I: embryonic day 11.0 (more )
Note: 40-somite stage.
Structure Level Pattern Image Note
TS18: dorsal aorta Present Regionally restricted 3I Expression is in the aortic clusters and the aortic floor.
Specimen 4A: embryonic day 10.5 (more )
Note: 35-somite stage.
Structure Level Pattern Image Note
TS17: liver Present 4A
TS17: dorsal aorta Present Regionally restricted 4A Expression is in the aortic floor.
Specimen 4E: embryonic day 10.0 (more )
Note: 30-35 somites.
Structure Level Pattern Image Note
TS16: 1st branchial arch Present 4E
TS16: 2nd branchial arch Present 4E
TS16: 3rd branchial arch Present 4E
TS16: 4th branchial arch Present 4E
Specimen 4F: embryonic day 10.0 (more )
Note: 30-35 somites.
Structure Level Pattern Image Note
TS16: 4th branchial pouch Present Regionally restricted 4F Expression is in the mesenchyme.
TS16: 3rd branchial pouch Absent 4F There is no expression in the thymic epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory