Kit RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:13166 Duttlinger R, et al., W-sash affects positive and negative elements controlling c-kit expression: ectopic c-kit expression at sites of kit-ligand expression affects melanogenesis. Development. 1993 Jul;118(3):705-17
Assay type:	RNA in situ
MGI Accession ID:	MGI:1350937
Gene symbol:	Kit
Gene name:	KIT proto-oncogene receptor tyrosine kinase

Probe:	Kit probe4
Probe preparation:	Antisense labelled with S35 RNA
Visualized with:	Autoradiography

Results

2A/E ©

Specimen 2A/E: embryonic day 13.5 (more

)
Note: This section is at the level of the lung.

Structure	Level	Pattern	Image	Note
TS21: skin	Present	Regionally restricted	2A/E	Expression is in melanoblasts.
TS21: left lung lobar bronchus mesenchyme	Present		2A/E
TS21: right lung accessory lobe lobar bronchus mesenchyme	Present		2A/E

2C/G ©

Specimen 2C/G: embryonic day 13.5 (more

)
Note: This cross-section is at the level of the testis.

Structure	Level	Pattern	Image	Note
TS21: skin	Present	Regionally restricted	2C/G	Expression is in melanoblasts.

2K/L ©

Specimen 2K/L: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: gut	Present	Regionally restricted	2K/L	Expression is in the mesenchymal layer.

2B/F ©

Specimen 2B/F: embryonic day 13.5; Kit^W-sh/Kit^W-sh (more

)
Note: This section is at the level of the lung.

Structure	Level	Pattern	Image	Note
TS21: skin	Absent		2B/F

2D/H ©

Specimen 2D/H: embryonic day 13.5; Kit^W-sh/Kit^W-sh (more

)
Note: This section is at the level of the testis.

Structure	Level	Pattern	Image	Note
TS21: skin	Absent		2D/H

2I/J ©

Specimen 2I/J: embryonic day 13.5; Kit^W-sh/Kit^W-sh (more

)

Structure	Level	Pattern	Image	Note
TS21: testis	Present		2I/J
TS21: gut	Absent		2I/J	There is no expression in the mesenchymal layer.

3A/D ©

Specimen 3A/D: embryonic day 10.5 (more

)

Structure	Level	Image
TS17: neural tube floor plate	Absent	3A/D
TS17: otocyst mesenchyme	Absent	3A/D
TS17: tail dermomyotome	Absent	3A/D
TS17: trunk dermomyotome	Absent	3A/D

3G/J ©

Specimen 3G/J: embryonic day 10.5 (more

)

Structure	Level	Image
TS17: neural tube floor plate	Absent	3G/J
TS17: otocyst mesenchyme	Absent	3G/J
TS17: tail dermomyotome	Absent	3G/J
TS17: trunk dermomyotome	Absent	3G/J

3B/E ©

Specimen 3B/E: embryonic day 10.5; Kit^W-sh/Kit^W-sh (more

)

Structure	Level	Pattern	Image	Note
TS17: otocyst mesenchyme	Present		3B/E	Expression is ectopic.
TS17: neural tube floor plate	Present	Regionally restricted	3B/E	Ectopic expression extends anteriorly to the floorplate of the myelencephalon.

3H/K ©

Specimen 3H/K: embryonic day 10.5; Kit^W-sh/Kit^W-sh (more

)

Structure	Level	Pattern	Image	Note
TS17: tail dermomyotome	Present	Regionally restricted	3H/K	Ectopic expression is in the dermatome except in the most recently formed caudal somites.
TS17: trunk dermomyotome	Present	Regionally restricted	3H/K	Ectopic expression is in the dermatome except in the most recently formed caudal somites.
TS17: neural tube floor plate	Present	Regionally restricted	3H/K	Ectopic expression extends anteriorly to the floorplate of the myelencephalon.

4E ©

Specimen 4E: embryonic day 10.5; Kit^W-sh/Kit^W-sh (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present	Uniform	4E	This represents ectopic expression in this mutant.

4F ©

Specimen 4F: embryonic day 10.5; Kit^W-sh/Kit^W-sh (more

)

Structure	Level	Pattern	Image	Note
TS17: trunk dermomyotome	Present	Uniform	4F	Ectopic expression in this mutant is in the dermatome.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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