Gene Expression Data
Assay Details
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Assay
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Reference:
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J:41540
Rossel M, et al., Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development. 1999 Nov;126(22):5027-40
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1346702
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Gene symbol:
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Tfap2a
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Gene name:
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transcription factor AP-2, alpha
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Results
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Specimen
5E:
(close  )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Hoxa1tm1Mrc/Hoxa1+
Hoxb1tm3Mrc/Hoxb1+
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Age:
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embryonic day 9.25-9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: migrating neural crest |
Present |
Single cells |
5E
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Three populations of neural crest, labeled with AP-2, can be viewed in the brancial arch region migrating into the three branchial arches.
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Specimen
5F:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Hoxa1tm1Mrc/Hoxa1tm1Mrc
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Age:
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embryonic day 9.25-9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: migrating neural crest |
Present |
Single cells |
5F
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The amount of AP-2-labeled neural crest migrating into the branchial arches appears fairly normal in this mutant. A slight reduction of labeled cells migrating into the 2nd branchial arch is apparent.
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Specimen
5G:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Hoxa1tm1Mrc/Hoxa1tm1Mrc
Hoxb1tm3Mrc/Hoxb1+
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Age:
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embryonic day 9.25-9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: migrating neural crest |
Present |
Single cells |
5G
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Only two populations of neural crest migrating into the 1st and 3rd arch are visible in this mutant.
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Specimen
5H:
(close )
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: migrating neural crest |
Present |
Single cells |
5H
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Only two populations of neural crest migrating into the 1st and 3rd arch are visible in this mutant.
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Analysis Tools
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