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Gene Expression Data
Assay Details
Assay
Reference: J:53656 Perea-Gomez A, et al., HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo. Development. 1999 Oct;126(20):4499-511
Assay type: RNA in situ
MGI Accession ID: MGI:1346180
Gene symbol: Lhx1
Gene name: LIM homeobox protein 1
Probe: Lhx1 cDNA1
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen 1.B: embryonic day 5.5 (more )
Structure Level Pattern Image Note
TS8: extraembryonic visceral endoderm Present Regionally restricted 1B Expression is found exclusively in the visceral endoderm in contact with the epiblast.
Specimen 1.E: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 1E
TS9: primitive streak Present 1E
TS9: extraembryonic visceral endoderm Present Regionally restricted 1E Expression is progressively restricted to the anterior visceral endoderm and can no longer be detected in the region of the visceral endoderm overlying the primitive streak.
TS9: embryo mesoderm Present Regionally restricted 1E Expression is observed in mesoderm wings.
Specimen 1.G: embryonic day 6.25 (more )
Note: Double labeled: purple - Lhx1; brown - Foxa2 (assay MGI:1346356).
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 1G Lhx1 (Lim1) and Hnf3b are coexpressed in the anterior visceral endoderm and in the anterior primitive streak.
TS9: primitive streak Present 1G Lhx1 (Lim1) and Hnf3b are coexpressed in the anterior visceral endoderm and in the anterior primitive streak.
Specimen 1.H: embryonic day 6.5 (more )
Note: Double labeled: purple - Lhx1; brown - Foxa2 (assay MGI:1346356).
Structure Level Pattern Image Note
TS9: primitive streak Present Regionally restricted 1H Expression domain is encompassed by the domain of expression of Hnf3b in the anterior primitive streak.
Specimen 1.I: embryonic day 7.5 (more )
Note: Double labeled: purple - Lhx1; brown - Foxa2 (assay MGI:1346356).
Structure Level Pattern Image Note
TS11: node Present 1I
TS11: notochordal process Present 1I
Specimen 1.J: embryonic day 6.25 (more )
Note: Double labeled: purple - Lhx1; brown - Foxa2 (assay MGI:1346356).
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 1J Lhx1 (Lim1) and Hnf3b are coexpressed in the anterior visceral endoderm and in the anterior primitive streak.
TS9: primitive streak Present 1J Lhx1 (Lim1) and Hnf3b are coexpressed in the anterior visceral endoderm and in the anterior primitive streak.
Specimen 1.K: embryonic day 6.5 (more )
Note: Double labeled: purple - Lhx1; brown - Foxa2 (assay MGI:1346356).
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 1K Lhx1 (Lim1) and Hnf3b are coexpressed in the anterior visceral endoderm and in the anterior primitive streak.
TS9: primitive streak Present 1K Lhx1 (Lim1) and Hnf3b are coexpressed in the anterior visceral endoderm and in the anterior primitive streak.
Specimen 1.L: embryonic day 7.5 (more )
Note: Double labeled: purple - Lhx1; brown - Foxa2 (assay MGI:1346356).
Structure Level Pattern Image Note
TS11: node Present Regionally restricted 1L A large number of cells in these regions also express Hnf3b.
TS11: notochordal process Present Regionally restricted 1L A large number of cells in these regions also express Hnf3b.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory