About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:20161 George KM, et al., Embryonic expression and cloning of the murine GATA-3 gene. Development. 1994 Sep;120(9):2673-86
Assay type: RNA in situ
MGI Accession ID: MGI:1344659
Gene symbol: Gata3
Gene name: GATA binding protein 3
Probe: mc5b
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: The probe does not contain sequences corresponding to the zinc fingers of mGATA-3 to preclude the possibility of cross hybridization to other members of the GATA factor family.
Results
Specimen 1A,1B: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: embryo Absent 1A , 1B

Specimen 1C,1D: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: ectoplacental cone Strong 1D , 1C
TS12: primary trophoblast giant cell Strong 1D , 1C

Specimen 1E: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: central nervous system Present 1E mGATA-3 is expressed at varying levels throughout the CNS.
TS16: trunk somite Present 1E

Specimen 1F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 1F Expression is detected in the anterior end of the telencephalon.
TS17: otocyst Present 1F
TS17: peripheral nervous system Present Regionally restricted 1F Expression is detected in the ganglia of the PNS.
TS17: acoustic ganglion Present 1F
TS17: facial ganglion Present 1F
TS17: trigeminal ganglion Present 1F
TS17: eye Present 1F

Specimen 1G: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: central nervous system Present 1G mGATA-3 is expressed at varying levels throughout the CNS.
TS16: eye Present 1G

Specimen 1H: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: central nervous system Present 1H mGATA-3 is expressed at varying levels throughout the CNS.
TS16: trunk somite Present 1H
TS16: mesonephros Present 1H

Specimen 2A,2B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: central nervous system Present 2A , 2B Expression was diffuse throughout much of the CNS.
TS19: midbrain Present Regionally restricted 2B , 2A Expression was localized within the walls of the midbrain.
TS19: metencephalon basal plate Present 2A , 2B

Specimen 2C,2D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 2D , 2C
TS19: future spinal cord Present 2D , 2C
TS19: heart Present 2D , 2C
TS19: liver Present 2D , 2C
TS19: mesonephros Present 2D , 2C
TS19: sympathetic ganglion Present 2D , 2C
TS19: extraembryonic venous system Present Regionally restricted 2D , 2C Expression is present in the vitelline vein.

Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted Expression continues in the otic vesicle.
TS19: peripheral nervous system Present Regionally restricted Expression continues in many ganglia of the PNS.

Specimen 2E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain Present Regionally restricted 2E Expression accumulates in the outer half.

Specimen 2F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pons Present Regionally restricted 2F Expression becomes restricted to two bilaterally symmetric groups of cells in both halves of the diencephalon.

Specimen 2G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: sympathetic ganglion Present 2G
TS20: dorsal root ganglion Absent 2G
TS20: spinal cord Present Regionally restricted 2G Expression in the spinal cord is restricted to the ventral half.

Specimen 3A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: diencephalon Present 3A
TS22: pons Present Regionally restricted 3A Expression in the pons is even more spatially restricted than at e12.5.
TS22: midbrain Present Regionally restricted 3A Expression remains removed from the immediate layer of cells overlying the ventricle.

Specimen 3B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: vomeronasal organ Present 3B

Specimen 3C,3D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adrenal medulla Present 3D , 3C
TS22: maturing glomerular tuft Present 3D , 3C

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord Weak Regionally restricted Expression is not detected in the spinal cord at the approximate level of the most rostral cervical vertebra, but is detected in more caudal sections in the ventral half of the spinal cord at significantly lower levels than on previous days of development
TS22: cranial ganglion Present
TS22: inner ear Present
TS22: sympathetic ganglion Present
TS22: thymus primordium Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory