About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:49251 Matise MP, et al., Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development. 1998 Aug;125(15):2759-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1342456
Gene symbol: Shh
Gene name: sonic hedgehog
Antibody: Anti-Shh
Detection system: Secondary antibody
Results
Specimen 1.A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present 1A Expression was detected in the ventral midline in the spinal cord.
TS17: hindbrain Present 1A Expression was detected in the ventral midline in the midbrain and hindbrain.
TS17: midbrain Present 1A Expression was detected in the ventral midline in the midbrain and hindbrain.

Specimen 1.B: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: future spinal cord Absent 1B Expression was not detected in the ventral midline in the spinal cord.
TS17: hindbrain Absent 1B Expression was not detected in the ventral midline in the midbrain and hindbrain.
TS17: midbrain Absent 1B Expression was not detected in the ventral midline in the midbrain and hindbrain.

Specimen 8.E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: notochord Present 8E
TS15: future spinal cord Present 8E

Specimen 8.F: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS15: notochord Present 8F Expression is restricted to the notochord.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory