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Gene Expression Data
Assay Details
Assay
Reference: J:49251 Matise MP, et al., Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development. 1998 Aug;125(15):2759-70
Assay type: RNA in situ
MGI Accession ID: MGI:1342117
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA2
Probe preparation: Antisense RNA
Results
Specimen 1.C: embryonic day 8.5 (more )
Note: 10 somite stage.
Structure Level Pattern Image Note
TS13: future prosencephalon Present 1C
TS13: notochord Present 1C
Specimen 1.D: embryonic day 8.5; Gli2tm1Alj/Gli2tm1Alj (more )
Note: 10 somite stage.
Structure Level Pattern Image Note
TS13: notochord Present 1D
TS13: future brain Absent 1D Expression had not yet initiated in the CNS in this 10-somite mutant embryo.
TS13: future spinal cord Absent 1D Expression had not yet initiated in the CNS in this 10-somite mutant embryo.
Specimen 1.E: embryonic day 8.5 (more )
Note: 10 somite stage.
Structure Level Pattern Image Note
TS13: future prosencephalon Present 1E
Specimen 1.F: embryonic day 8.5; Gli2tm1Alj/Gli2tm1Alj (more )
Note: 10 somite stage.
Structure Level Pattern Image Note
TS13: future prosencephalon Absent 1F
TS13: notochord Present 1F
Specimen 1.G: embryonic day 8.5; Gli2tm1Alj/Gli2tm1Alj (more )
Note: 12 somite stage.
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 1G Expression was delayed in this 12-somite mutant embryo.
TS13: notochord Present 1G
Specimen 1.H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 1H
TS15: future hindbrain Present 1H
TS15: future midbrain Present 1H
TS15: future spinal cord Present 1H
Specimen 1.I: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 1I Expression was similar to that seen in the wild-type.
TS15: future hindbrain Absent 1I
TS15: future midbrain Absent 1I
TS15: future spinal cord Absent 1I
Specimen not shown: embryonic day 8.0; Gli2tm1Alj/Gli2tm1Alj (more )
Note: 7 somite stage.
Structure Level Pattern Image Note
TS12: notochord Present
TS12: neural ectoderm Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory