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Gene Expression Data
Assay Details
Assay
Reference: J:21111 Hebrok M, et al., M-twist is an inhibitor of muscle differentiation. Dev Biol. 1994 Oct;165(2):537-44
Assay type: RNA in situ
MGI Accession ID: MGI:1341129
Gene symbol: Twist1
Gene name: twist basic helix-loop-helix transcription factor 1
Probe: M-twist cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present Regionally restricted M-twist was widely expressed in the mouse embryo at day 10.5 p.c., except in areas where myf5 is expressed.

Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk dermomyotome Present 1A/B M-twist is expressed in the dermatome, but not in the myotome.
TS17: trunk sclerotome Present 1A/B

Specimen 1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk dermomyotome Present Regionally restricted 1D/E M-twist is expressed in the dermatome, but not in the myotome.
TS17: trunk sclerotome Present 1D/E

Specimen 1H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Strong Regionally restricted 1G/H M-twist is highly expressed in the developing limb buds but is not detectable in areas where myf5 is found.

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo Present Regionally restricted M-twist was widely expressed in the mouse embryo at day 12.5 p.c., except in areas where myf5 is expressed.

Specimen 2B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral region Present Regionally restricted 2A/B The expression domains of M-twist and myf5 are mutually exclusive in the developing branchial arches, where M-twist is not observed in the myf5-expressing anlagen of the jaw muscles.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory