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Gene Expression Data
Assay Details
Assay
Reference: J:54746 Matise MP, et al., Ventral midline cells are required for the local control of commissural axon guidance in the mouse spinal cord. Development. 1999 Aug;126(16):3649-59
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1340853
Gene symbol: Cntn2
Gene name: contactin 2
Antibody: anti-TAG-1 (4D7)
Detection system: Secondary antibody
Results
Specimen 2.C: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: future spinal cord Present Regionally restricted 2C Expression is detected on commissural axons.

Specimen 2.F: embryonic day 11.0; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS18: future spinal cord Present Regionally restricted 2F

Specimen 5.C: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: future spinal cord Present Regionally restricted 5C Expression is seen on commissural axons projecting ventrally towards the floor plate, but decreases as axons cross the midline in the ventral commissure; no expression is seen on longitudinal axons in the ventral funiculus.

Specimen 5.D: embryonic day 11.0; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS18: future spinal cord Present Regionally restricted 5D As in wild-type, expression is seen on commissural axons projecting ventrally towards the midline. In contrast to wild-type, expression was also seen on the (rare) longitudinally directed commissural axon.

Specimen 5.G: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: future spinal cord Present Regionally restricted 5G Expression is seen on commissural axons projecting ventrally towards the floor plate, but decreases as axons cross the midline in the ventral commissure; no expression is seen on longitudinal axons in the ventral funiculus.

Specimen 5.H: embryonic day 11.0; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS18: future spinal cord Present Regionally restricted 5H As in wild-type, expression is seen on commissural axons projecting ventrally towards the midline. In contrast to wild-type, expression was also seen on the (rare) longitudinally directed commissural axon.

Specimen 5.I: embryonic day 11.0; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS18: future spinal cord Present Regionally restricted 5I As in wild-type, expression is seen on commissural axons projecting ventrally towards the midline. In contrast to wild-type, expression was also seen on the (rare) longitudinally directed commissural axon.

Specimen not shown: embryonic day 10.0-11.0 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted Expression was detected on dorsal commissural cells in the spinal cord and hindbrain.
TS17: hindbrain Present Regionally restricted Expression was detected on dorsal commissural cells in the spinal cord and hindbrain.

Specimen not shown: embryonic day 10.0-11.0; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted Expression was detected on dorsal commissural cells in the spinal cord and hindbrain. Expression pattern was similar to that in the wild-type.
TS17: hindbrain Present Regionally restricted Expression was detected on dorsal commissural cells in the spinal cord and hindbrain. Expression pattern was similar to that in the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory