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Gene Expression Data
Assay Details
Assay
Reference: J:56093 Bruneau BG, et al., Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome. Dev Biol. 1999 Jul 1;211(1):100-8
Assay type: RNA in situ
MGI Accession ID: MGI:1340489
Gene symbol: Tbx5
Gene name: T-box 5
Probe: Tbx5 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 8.0 (more )
Note: Two-somite embryo. Frontal view.
Structure Level Pattern Image Note
TS12: heart Present Regionally restricted 2A Expression is in the cardiac cresent.
Specimen 2B: embryonic day 8.25 (more )
Note: Ventral view.
Structure Level Pattern Image Note
TS12: common atrial chamber Strong 2B Expression was robust in the very posterior portion of the heart, which is destined to become the sinus venosa and the atria.
TS12: sinus venosus Strong 2B Expression was robust in the very posterior portion of the heart, which is destined to become the sinus venosa and the atria.
TS12: primitive heart tube cardiac muscle Present Regionally restricted 2B Expression is in the myocardium that encircles the endocardial tube.
Specimen 2C: embryonic day 8.5 (more )
Note: Ventral view.
Structure Level Pattern Image Note
TS13: common atrial chamber Present 2C Expression was localized exclusively in the posterior structures of the heart that give rise to the atria and the sinus venosa.
TS13: sinus venosus Present 2C Expression was localized exclusively in the posterior structures of the heart that give rise to the atria and the sinus venosa.
Specimen 2D: embryonic day 8.5 (more )
Note: Right side lateral view.
Structure Level Pattern Image Note
TS12: common atrial chamber Present 2D Expression was localized exclusively in the posterior structures of the heart that give rise to the atria and the sinus venosa.
TS12: sinus venosus Present 2D Expression was localized exclusively in the posterior structures of the heart that give rise to the atria and the sinus venosa.
Specimen 2E: embryonic day 9.0 (more )
Note: Viewed from the right side.
Structure Level Pattern Image Note
TS14: primitive ventricle Present Regionally restricted 2E Originally expression is in the entire ventricle, but when the ventricles adopt a left-right arrangement, expression is restricted to the left side of the ventricles.
Specimen 2F: embryonic day 9.0 (more )
Note: Viewed from the left side.
Structure Level Pattern Image Note
TS14: primitive ventricle Present Regionally restricted 2F Expression is restricted to the left side of the ventricles.
Specimen 2G: embryonic day 9.0 (more )
Note: Viewed ventrally.
Structure Level Pattern Image Note
TS14: primitive ventricle Present Regionally restricted 2G Expression is restricted to the left side of the ventricles.
Specimen 2H: embryonic day 9.5 (more )
Note: Viewed from the left side.
Structure Level Pattern Image Note
TS15: eye Present 2H
TS15: forelimb bud Present 2H
TS15: primitive ventricle Present Regionally restricted 2H Expression is restricted to the left side of the ventricles.
Specimen 2I: embryonic day 11.5 (more )
Note: Viewed from the front.
Structure Level Pattern Image Note
TS19: heart right ventricle Trace 2I
TS19: outflow tract Trace 2I
TS19: heart left ventricle Present 2I
Specimen 2J: embryonic day 11.5 (more )
Note: Viewed from the back.
Structure Level Pattern Image Note
TS19: heart right ventricle Trace 2J
TS19: outflow tract Trace 2J
TS19: heart left ventricle Present 2J
Specimen 2K: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: eye Present 2K
TS19: forelimb bud Present 2K
TS19: heart Present 2K
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
MGI 6.24 		The Jackson Laboratory