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Gene Expression Data
Assay Details
Assay
Reference: J:51570 Furuta Y, et al., BMP4 is essential for lens induction in the mouse embryo. Genes Dev. 1998 Dec 1;12(23):3764-75
Assay type: RNA in situ
MGI Accession ID: MGI:1339914
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Probe: Sox2 cDNA5
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1. E.: embryonic day 9.0 (more )
Note: Embryo is 18 somite stage.
Structure Level Pattern Image Note
TS14: eye Trace 1E
Specimen 1. F.: embryonic day 9.5 (more )
Note: Embryo is 21 somite stage.
Structure Level Pattern Image Note
TS15: optic vesicle Present 1F
TS15: eye Weak Regionally restricted 1F Expression is detected in the ectoderm of the presumptive eye.
Specimen 1. G.: embryonic day 9.5 (more )
Note: Embryo is 24 somite stage.
Structure Level Pattern Image Note
TS15: lens placode Strong Regionally restricted 1G Expression was detected in the presumptive lens ectoderm at the site of contact with the optic vesicle.
Specimen 1. H.: embryonic day 11.0 (more )
Note: Embryo is ~40 somite stage.
Structure Level Pattern Image Note
TS18: lens vesicle Strong 1H
Specimen 1. I.: embryonic day 9.5; Pax6Sey-Neu/Pax6Sey-Neu (more )
Note: Embryo is 27 somite stage.
Structure Level Pattern Image Note
TS15: eye Present 1I Expression is less than in wild-type.
Specimen 3. D.: embryonic day 9.5; Pax6Sey-Neu/Pax6Sey-Neu (more )
Note: Embryo is 22-24 somite stage.
Structure Level Pattern Image Note
TS15: lens placode Strong Regionally restricted 3D Expression is detected in the presumptive lens ectoderm.
Specimen 3. H.: embryonic day 9.5; Bmp4tm1Blh/Bmp4tm1Blh (more )
Note: Embryo is 22-25 somite stage.
Structure Level Pattern Image Note
TS15: lens placode Absent 3H Expression is absent from the presumptive lens ectoderm.
TS15: optic vesicle Absent 3H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory