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Gene Expression Data
Assay Details
Assay
Reference: J:30825 Sporle R, et al., Severe defects in the formation of epaxial musculature in open brain (opb) mutant mouse embryos. Development. 1996 Jan;122(1):79-86
Assay type: RNA in situ
MGI Accession ID: MGI:1336671
Gene symbol: Myog
Gene name: myogenin
Probe: Myog cDNA18
Probe preparation: Antisense RNA
Results
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: skeletal muscle Strong

Specimen 3A: embryonic day 11.5 (more )
Note: 3A is at the upper thoracic level.
Structure Level Pattern Image Note
TS19: body wall mesenchyme Present Regionally restricted 3A Expression is in the developing musculature.

Specimen 3B: embryonic day 11.5; Rab23opb/Rab23opb (more )
Note: 3B is at the upper thoracic level.
Structure Level Pattern Image Note
TS19: body wall mesenchyme Present Regionally restricted 3B Expression in lower cervical and upper thoracic regions of mutants shows a severe reduction in formation of dorsal muscle, but formation of ventral musculature and intercostal muscle was not impaired.

Specimen 3C: embryonic day 11.5 (more )
Note: 3C is at the lower thoracic level.
Structure Level Pattern Image Note
TS19: body wall mesenchyme Present Regionally restricted 3C Expression is in the developing musculature.

Specimen 3D: embryonic day 11.5; Rab23opb/Rab23opb (more )
Note: 3D is at the lower thoracic level.
Structure Level Pattern Image Note
TS19: body wall mesenchyme Present Regionally restricted 3D Expression in lower thoracic regions of mutants shows almost no dorsal musculature, but formation of ventral musculature and intercostal muscle was not impaired.

Specimen 3E: embryonic day 11.5 (more )
Note: 3E is at the lumbar/hindlimb level.
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present Regionally restricted 3E Expression is in the developing musculature.

Specimen 3F: embryonic day 11.5; Rab23opb/Rab23opb (more )
Note: 3F is at the lumbar/hindlimb level.
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present Regionally restricted 3F Expression shows formation of limb muscle was not impaired.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory