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Gene Expression Data
Assay Details
Assay
Reference: J:30829 McLaughlin KJ, et al., Mouse embryos with paternal duplication of an imprinted chromosome 7 region die at midgestation and lack placental spongiotrophoblast. Development. 1996 Jan;122(1):265-70
Assay type: RNA in situ
MGI Accession ID: MGI:1336238
Gene symbol: Ascl2
Gene name: achaete-scute family bHLH transcription factor 2
Probe: PBSMash2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Mash2 is contained within the duplication on chromosome 7. Please refer to the original manuscript for the exact breeding protocol.
Results
Specimen 3D: embryonic day 9.5; T(7;15)9H/T(7;15)9H+ (more )
Note: The duplication on chromosome 7 was introduced maternally.
Structure Level Pattern Image Note
TS15: extraembryonic component Present 3D Expression in this mutant is the same as in wild-type embryos.
TS28: placenta Present 3D Expression in this mutant is the same as in wild-type embryos.
Specimen 3E: embryonic day 9.5; T(7;15)9H/T(7;15)9H+ (more )
Note: The duplication on chromosome 7 was introduced paternally.
Structure Level Pattern Image Note
TS15: extraembryonic component Absent 3E
TS28: placenta Absent 3E
Specimen 3F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 3F
TS28: placenta Present 3F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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