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Gene Expression Data
Assay Details
Assay
Reference: J:38385 Conway SJ, et al., Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp2H) mutant. Development. 1997 Jan;124(2):505-14
Assay type: RNA in situ
MGI Accession ID: MGI:1335054
Gene symbol: Hoxa3
Gene name: homeobox A3
Probe: Mo-10 probe2
Probe preparation: Antisense RNA
Results
Specimen 9A: embryonic day 10.5 (more )
Note: Control embryo was either Sp2H/+ or +/+.
Structure Level Pattern Image Note
TS17: 3rd branchial arch Present Regionally restricted 9A Hoxa3 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
TS17: 4th branchial arch Present Regionally restricted 9A Hoxa3 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
TS17: 6th branchial arch Present Regionally restricted 9A Hoxa3 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
TS17: outflow tract Present Regionally restricted 9A Hoxa3 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
TS17: neural tube Present Regionally restricted 9A The anterior limit of Hoxa3 expression in the neural tube was at the boundary between rhombomeres 4 and 5.
TS17: 1st branchial arch Present 9A
TS17: 2nd branchial arch Present 9A
TS17: limb Present 9A Expression was seen in the limb bud.

Specimen 9B: embryonic day 10.5; Pax3Sp-2H/Pax3Sp-2H (more )
Structure Level Pattern Image Note
TS17: 3rd branchial arch Weak Regionally restricted 9B The stream of cells expressing Hoxa3 was considerably reduced in mutant embryos.
TS17: 4th branchial arch Weak Regionally restricted 9B The stream of cells expressing Hoxa3 was considerably reduced in mutant embryos.
TS17: 6th branchial arch Weak Regionally restricted 9B The stream of cells expressing Hoxa3 was considerably reduced in mutant embryos.
TS17: outflow tract Weak Regionally restricted 9B The stream of cells expressing Hoxa3 was considerably reduced in mutant embryos.
TS17: neural tube Present Regionally restricted 9B Expression in this mutant is the same as in wild-type embryos, although the intensity of expression in the occipital and cervical regions was reduced.
TS17: 1st branchial arch Present 9B Expression in this mutant is the same as in wild-type embryos, although the intensity of expression in the branchial arches was reduced.
TS17: 2nd branchial arch Present 9B Expression in this mutant is the same as in wild-type embryos, although the intensity of expression in the branchial arches was reduced.
TS17: limb Present 9B Expression in this mutant is the same as in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory