Fgf8 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:38380 Kuhlman J, et al., Limb deformity proteins: role in mesodermal induction of the apical ectodermal ridge. Development. 1997 Jan;124(1):133-9
Assay type:	RNA in situ
MGI Accession ID:	MGI:1332449
Gene symbol:	Fgf8
Gene name:	fibroblast growth factor 8

Probe:	Fgf8 cDNA13
Probe preparation:	RNA

Results

Specimen not shown: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: forelimb bud ectoderm	Present	Regionally restricted		Fgf8 was expressed in a stripe that prefigures the ridge.
TS15: hindlimb ridge ectoderm	Present	Regionally restricted		Fgf8 was expressed in a stripe that prefigures the ridge.

Specimen not shown: embryonic day 9.5; Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} (more

)
Note: limb deformity

Structure	Level	Pattern	Image	Note
TS15: forelimb bud ectoderm	Present	Regionally restricted		Fgf8 was expressed in a stripe that prefigures the ridge.
TS15: hindlimb ridge ectoderm	Present	Regionally restricted		Fgf8 was expressed in a stripe that prefigures the ridge.

1C ©

Specimen 1C: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud apical ectodermal ridge	Strong		1C
TS17: hindlimb bud apical ectodermal ridge	Strong		1C

1D ©

Specimen 1D: embryonic day 10.5; Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} (more

)
Note: limb deformity

Structure	Level	Pattern	Image	Note
TS17: forelimb bud apical ectodermal ridge	Moderate		1D	Fgf8 was expressed at slightly reduced levels and often displayed a patchy appearance.
TS17: hindlimb bud apical ectodermal ridge	Moderate		1D	Fgf8 was expressed at slightly reduced levels and often displayed a patchy appearance.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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