About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:45779 Jernvall J, et al., The life history of an embryonic signaling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot. Development. 1998 Jan;125(2):161-9
Assay type: RNA in situ
MGI Accession ID: MGI:1332266
Gene symbol: Cdkn1a
Gene name: cyclin dependent kinase inhibitor 1A
Probe: p21 probe
Probe preparation: labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1 left: embryonic day 13.0 (more )
Note: Bud stage; initiation.
Structure Level Pattern Image Note
TS21: lower jaw molar Present Regionally restricted 1_p21 left
Specimen 1 right: embryonic day 14.0 (more )
Note: Cap stage; fully formed.
Structure Level Pattern Image Note
TS22: lower jaw molar enamel organ Present Uniform 1_p21 right
Specimen 3 top: embryonic day 14.0 (more )
Note: Cap stage.
Structure Level Pattern Image Note
TS22: lower jaw molar enamel organ Present Uniform 3_p21 top
Specimen 3 bottom: embryonic day 14.5-15.0 (more )
Note: Late cap stage.
Structure Level Pattern Image Note
TS22: enamel knot Present Regionally restricted 3_p21 bottom The distal part of the knot has disappeared and no transcripts are present in this area. The remaining half (mesial) of the enamel knot continues to express p21.
TS22: lower jaw molar enamel organ Present Regionally restricted 3_p21 bottom The distal part of the knot has disappeared and no transcripts are present in this area. The remaining half (mesial) of the enamel knot continues to express p21.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory