Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:49653
Yang Y, et al., Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling. Development. 1998 Aug;125(16):3123-32
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:1331145
|
|
Gene symbol:
|
Ptch1
|
|
Gene name:
|
patched 1
|
|
Probe:
|
M2-3
|
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
|
|
Results
|
Specimen
5A:
embryonic day 11.5
(more  )
Specimen
5A:
(close  )
|
Genetic Background:
|
involves: 101/H * C3H/HeH
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
Specimen
5B:
embryonic day 11.5; Dbf/Dbf +
(more )
Specimen
5B:
(close )
|
Genetic Background:
|
involves: 101/H * C3H/HeH
|
|
Mutant Allele(s):
|
Dbf/Dbf+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: forelimb bud |
Present |
Graded |
5B
|
Expression is ectopically activated in the distal limb across the A-P axis. Ptc expression extended all the way to the anterior limb margin. Ptc expression is stronger at the distal-anterior limb margin.
|
| TS19: branchial arch |
Present |
|
5B
|
Expression is ectopically activated in the facial processes.
|
| TS19: hindlimb bud |
Present |
Regionally restricted |
5B
|
Expressiontc is ectopically activated in the distal limb across the A-P axis and in the future femur region. Ptc expression extended all the way to the anterior limb margin.
|
|
Analysis Tools