Gene Expression Data
Assay Details
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Assay
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Reference:
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J:49252
Hardcastle Z, et al., The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants. Development. 1998 Aug;125(15):2803-11
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1320902
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Gene symbol:
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Gli1
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Gene name:
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GLI-Kruppel family member GLI1
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Probe:
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Gli1 cDNA6
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Probe preparation:
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Antisense labelled with S35 RNA
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Results
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Specimen
1D:
embryonic day 11.5
(more  )
Specimen
1D:
(close  )
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Genetic Background:
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CD-1
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: mandibular process |
Present |
Regionally restricted |
1D
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The expression of Gli1 was similar to Ptc expression.
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| TS19: maxillary process |
Present |
Regionally restricted |
1D
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The expression of Gli1 was similar to Ptc expression.
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Specimen
1J:
embryonic day 12.5
(more )
Note: Early tooth bud stage.
Specimen
1J:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Early tooth bud stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: mandibular process |
Moderate |
Regionally restricted |
1J
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Gli1 was expressed in the odontogenic epithelium and mesenchyme of the incisors, whereas in the molars the medial pattern of expression was maintained. Gli1 expression was slightly lower than that of Ptc.
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| TS20: maxillary process |
Moderate |
Regionally restricted |
1J
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Gli1 was expressed in the odontogenic epithelium and mesenchyme of the incisors, whereas in the molars the medial pattern of expression was maintained. Gli1 expression was slightly lower than that of Ptc.
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Specimen
1P:
embryonic day 13.5
(more )
Specimen
1P:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: lower jaw incisor |
Present |
Regionally restricted |
1P
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In the maxillary and mandibular incisors and in the molars, Gli1 was apparent in the dental papilla, part of the dental organ and in the dental follicle.
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| TS21: lower jaw molar |
Present |
Regionally restricted |
1P
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In the maxillary and mandibular incisors and in the molars, Gli1 was apparent in the dental papilla, part of the dental organ and in the dental follicle.
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| TS21: upper jaw incisor |
Present |
Regionally restricted |
1P
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In the maxillary and mandibular incisors and in the molars, Gli1 was apparent in the dental papilla, part of the dental organ and in the dental follicle.
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| TS21: upper jaw molar |
Present |
Regionally restricted |
1P
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In the maxillary and mandibular incisors and in the molars, Gli1 was apparent in the dental papilla, part of the dental organ and in the dental follicle.
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Specimen
1V:
embryonic day 14.5
(more )
Note: Cap stage.
Specimen
1V:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Cap stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: lower jaw molar |
Present |
Regionally restricted |
1V
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In the molars Gli1 was expressed in a region of the tooth germ that appeared to surround the area of the enamel that was marked by Shh expression.
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| TS22: upper jaw molar |
Present |
Regionally restricted |
1V
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In the molars Gli1 was expressed in a region of the tooth germ that appeared to surround the area of the enamel that was marked by Shh expression.
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| TS22: enamel organ |
Absent |
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1B'
,
1V
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Specimen
not shown:
embryonic day 14.5
(more )
Note: Cap stage.
Specimen
not shown:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Cap stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: lower jaw incisor |
Present |
Regionally restricted |
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Gli1 mRNA could be detected in the incisors in similar regions as at E13.5.
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| TS22: upper jaw incisor |
Present |
Regionally restricted |
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Gli1 mRNA could be detected in the incisors in similar regions as at E13.5.
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Specimen
8B:
embryonic day 13.5
(more )
Specimen
8B:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
8D:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Gli2tm1Alj/Gli2tm1Alj
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Age:
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embryonic day 14.0
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Sex:
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Not Specified
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Type:
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section
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Specimen
8F:
(close )
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Genetic Background:
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involves: C3H * CD-1
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Mutant Allele(s):
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Gli3Xt-J/Gli3Xt-J
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
8H:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1
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Mutant Allele(s):
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Gli2tm1Alj/Gli2tm1Alj
Gli3Xt-J/Gli3+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Analysis Tools