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Gene Expression Data
Assay Details
Assay
Reference: J:46641 Rhinn M, et al., Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification. Development. 1998 Mar;125(5):845-56
Assay type: RNA in situ
MGI Accession ID: MGI:1315075
Gene symbol: Pax2
Gene name: paired box 2
Probe: Pax2 cDNA3
Probe preparation: RNA
Results
Specimen 2C: embryonic day 8.25 (more )
Structure Level Pattern Image Note
TS12: future midbrain Present 2C Pax2 was expressed in a broad domain corresponding to the midbrain and anterior hindbrain.
TS12: future hindbrain Present Regionally restricted 2C Pax2 was expressed in a broad domain corresponding to the midbrain and anterior hindbrain.

Specimen 2C': embryonic day 8.25; Otx2tm1Sla/Otx2tm1Sla (more )
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted 2C' Pax2 was expressed in the mid-hindbrain region in mutant embryos, but the expression domain in mutant embryos is smaller in size presumably due to the absence of the midbrain.

Specimen 8A: embryonic day 8.0 (more )
Note: 0-4 somites.
Structure Level Pattern Image Note
TS12: future hindbrain Present 8A Pax2 is expressed in the mesencephalic-metencephalic region.
TS12: future midbrain Present 8A Pax2 is expressed in the mesencephalic-metencephalic region.

Specimen 8B: embryonic day 8.0 (more )
Note: 6-8-somites.
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted 8B Pax2 is expressed in two separate domains in the forebrain and mesencephalon-metencephalon region of embryos.
TS12: future midbrain Present Regionally restricted 8B Pax2 is expressed in two separate domains in the forebrain and mesencephalon-metencephalon region of embryos.
TS12: future prosencephalon Present Regionally restricted 8B Pax2 is expressed in two separate domains in the forebrain and mesencephalon-metencephalon region of embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory