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Gene Expression Data
Assay Details
Assay
Reference: J:45576 Hadrys T, et al., Nkx5-1 controls semicircular canal formation in the mouse inner ear. Development. 1998 Jan;125(1):33-9
Assay type: RNA in situ
MGI Accession ID: MGI:1303353
Gene symbol: Hmx3
Gene name: H6 homeobox 3
Probe: probe 1
Probe preparation: Antisense RNA
Results
Specimen 1C WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: ear Strong 1C WT
TS19: hindbrain Strong 1C WT

Specimen 1C Nkx5-1 +/-: embryonic day 11.5; Hmx3tm1Ebo/Hmx3+ (more )
Structure Level Pattern Image Note
TS19: ear Moderate 1C Nkx5-1 +/-
TS19: hindbrain Moderate 1C Nkx5-1 +/-

Specimen 1C Nkx5-1 -/-: embryonic day 11.5; Hmx3tm1Ebo/Hmx3tm1Ebo (more )
Structure Level Pattern Image Note
TS19: embryo Absent 1C Nkx5-1 -/-

Specimen 4A 12S: embryonic day 8.5 (more )
Note: 12-somites.
Structure Level Pattern Image Note
TS13: future hindbrain Present 4A 12S The Nkx5-1 expression domain moves away from a position adjacent to the neural tube (12- and 26-somite stages) and becomes confined to the lateral wall of the closed otocyst (35-somite stage).
TS13: inner ear Present 4A 12S The Nkx5-1 expression domain moves away from a position adjacent to the neural tube (12- and 26-somite stages) and becomes confined to the lateral wall of the closed otocyst (35-somite stage).

Specimen 4A 26S: embryonic day 9.5 (more )
Note: 26-somites.
Structure Level Pattern Image Note
TS15: otocyst Present 4A 26S The Nkx5-1 expression domain moves away from a position adjacent to the neural tube (12- and 26-somite stages) and becomes confined to the lateral wall of the closed otocyst (35-somite stage).

Specimen 4A 35S: embryonic day 10.5 (more )
Note: 35-somites.
Structure Level Pattern Image Note
TS17: otocyst Present 4A 35S The Nkx5-1 expression domain moves away from a position adjacent to the neural tube (12- and 26-somite stages) and becomes confined to the lateral wall of the closed otocyst (35-somite stage).


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory