Gene Expression Data
Assay Details
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Assay
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Reference:
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J:43752
Xiang M, et al., Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells. Development. 1998 Oct;125(20):3935-46
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:1278430
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Gene symbol:
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Pvalb
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Gene name:
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parvalbumin
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Antibody:
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anti-parvalbumin
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin
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Results
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Specimen
5S:
(close  )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Mutant Allele(s):
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Pou4f3tm1Xia/Pou4f3+
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: inner ear |
Present |
Regionally restricted |
5S
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Expression was detected in the hair cell layer of the cochlear and vestibular systems.
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Specimen
5T:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Mutant Allele(s):
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Pou4f3tm1Xia/Pou4f3tm1Xia
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: inner ear |
Present |
Regionally restricted |
5T
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Expression was detected in the hair cell layer of the cochlear and vestibular systems and in a minor fraction of cells in the supporting cell layer. Expression was in a reduced number of cells compared to wild type.
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Specimen
6G:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Mutant Allele(s):
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Pou4f3tm1Xia/Pou4f3+
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: inner ear |
Present |
Regionally restricted |
6G
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Expression was detected in vestibular ganglia.
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Specimen
6H:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Mutant Allele(s):
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Pou4f3tm1Xia/Pou4f3tm1Xia
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: inner ear |
Present |
Regionally restricted |
6H
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Expression was detected in the vestibular ganglia, but the ganglia was reduced in size.
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Specimen
Not Shown:
embryonic day 15.5
(more  )
Specimen
Not Shown:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: inner ear |
Present |
Regionally restricted |
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Expression was detected in the spiral and vestibular ganglia.
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Specimen
Not Shown:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Mutant Allele(s):
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Pou4f3tm1Xia/Pou4f3tm1Xia
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: inner ear |
Present |
Regionally restricted |
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Expression was as detected in the wild type spiral and vestibular ganglia.
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Specimen
Not Shown:
postnatal day 5
(more )
Specimen
Not Shown:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Age:
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postnatal day 5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: inner ear |
Present |
Regionally restricted |
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Expression was detected in the spiral and vestibular ganglia.
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Specimen
Not Shown:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Mutant Allele(s):
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Pou4f3tm1Xia/Pou4f3tm1Xia
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Age:
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postnatal day 5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: inner ear |
Present |
Regionally restricted |
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Expression was detected in the spiral and vestibular ganglia, but the ganglia were reduced in size relative to wild type.
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Analysis Tools