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Gene Expression Data
Assay Details
Assay
Reference: J:49164 Ding Q, et al., Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development. 1998 Jul;125(14):2533-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1278429
Gene symbol: Foxa2
Gene name: forkhead box A2
Results
Specimen 2Q: embryonic day 8.0 (more )
Note: 2-somite stage. Specimen was fixed in PBS containing 3.7% formaldehyde.
Structure Level Pattern Image Note
TS12: notochord Present 2Q

Specimen 2R: embryonic day 8.0; Gli2tm1Alj/Gli2tm1Alj (more )
Note: 2-somite stage. Specimen was fixed in PBS containing 3.7% formaldehyde.
Structure Level Pattern Image Note
TS12: notochord Present 2R

Specimen 2S: embryonic day 8.0 (more )
Note: 2-somite stage. Specimen was fixed in PBS containing 3.7% formaldehyde.
Structure Level Pattern Image Note
TS12: future spinal cord neural plate Present 2S Expression is present in a broad domain, including the floor plate and some ventral neurons.
TS12: neural tube floor plate Present 2S Expression is present in a broad domain, including the floor plate and some ventral neurons.

Specimen 2T: embryonic day 8.5; Gli2tm1Alj/Gli2tm1Alj (more )
Note: 2-somite stage. Specimen was fixed in PBS containing 3.7% formaldehyde.
Structure Level Pattern Image Note
TS12: future spinal cord neural plate Absent 2T

Specimen 2U: embryonic day 9.0 (more )
Note: 15-somite stage. Specimen was fixed in PBS containing 3.7% formaldehyde.
Structure Level Pattern Image Note
TS14: notochord Present 2U

Specimen 2V: embryonic day 9.0; Gli2tm1Alj/Gli2tm1Alj (more )
Note: 15-somite stage. Specimen was fixed in PBS containing 3.7% formaldehyde.
Structure Level Pattern Image Note
TS14: notochord Present 2V
TS14: neural tube Present Spotted 2V Expressing cells could be found along the ventral midline of the neural tube.
TS14: future hindbrain Present Regionally restricted 2V In hindbrain and anterior spinal cord regions, large patches of expressing cells could be found. However, only few expressing cells were observed in the caudal part of the mutant spinal cord.
TS14: future spinal cord Present Regionally restricted 2V In hindbrain and anterior spinal cord regions, large patches of expressing cells could be found. However, only few expressing cells were observed in the caudal part of the mutant spinal cord.
TS14: prosencephalon Present Regionally restricted 2V Ventral forebrain expression could be clearly detected in the mutants.

Specimen 2W: embryonic day 9.5 (more )
Note: 25-somite stage. Specimen was fixed in PBS containing 3.7% formaldehyde.
Structure Level Pattern Image Note
TS15: notochord Present 2W

Specimen 2X: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj (more )
Note: 25-somite stage. Specimen was fixed in PBS containing 3.7% formaldehyde.
Structure Level Pattern Image Note
TS15: notochord Present 2X
TS15: neural tube Present Spotted 2X Patches of expressing cells could be found along the ventral midline of the neural tube.
TS15: tail neural tube Present Spotted 2X Patches of expressing cells could be found along the ventral midline of the neural tube.
TS15: future hindbrain Present Regionally restricted 2X In hindbrain and anterior spinal cord regions, large patches of expressing cells could be found. However, only few HNF3beta-positive cells were observed in the caudal part of the mutant spinal cord.
TS15: future spinal cord Present Regionally restricted 2X In hindbrain and anterior spinal cord regions, large patches of expressing cells could be found. However, only few HNF3beta-positive cells were observed in the caudal part of the mutant spinal cord.
TS15: tail future spinal cord Present Regionally restricted 2X In hindbrain and anterior spinal cord regions, large patches of expressing cells could be found. However, only few HNF3beta-positive cells were observed in the caudal part of the mutant spinal cord.
TS15: future forebrain Present Regionally restricted 2X Ventral forebrain expression could be clearly detected in the mutants.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory