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Antibody
Detail
Antibody
Name: anti-Cleaved Notch1 (Val1744) (D3B8) (#4147)
Host: rabbit
Type: Monoclonal
Class: IgG
Note: This antibody was obtained from Cell Signaling. Detects endogenous levels of the Notch1 intracellular domain (NICD) only when released by cleavage between Gly1753 and Val1754 (equivalent to Gly1743/ Val1744 of murine protein). The antibody does not recognize full-length Notch1 or Notch1 cleaved at other positions.
MGI Accession ID: MGI:5702631
Antigen
Name: cleaved Notch1
Species: human
Region covered: the sequence at the Val1754 cleavage site
Note: This sequence is equivalent to Val1744 in mouse.
Gene Notch1  notch 1
Expression Gene Expression Data (105 results)
References J:204466 Tadeu AM, et al., Development. 2013 Sep;140(18):3777-86
J:103603 Pan Y, et al., Dev Biol. 2005 Oct 15;286(2):472-82
J:208899 Williams DR, et al., Dev Biol. 2014 Apr 15;388(2):159-69
J:271577 Yu S, et al., Cell Stem Cell. 2018 Jul 5;23(1):46-59.e5
J:293446 Han S, et al., Development. 2018 Oct 1;145(19):dev157719
J:294646 Stupnikov MR, et al., Elife. 2019 Oct 21;8:e50487
J:306393 Ofek S, et al., BMC Biol. 2021 Apr 23;19(1):84
J:320419 Li R, et al., Dev Biol. 2022 Mar;483:89-97
J:325987 Bochter MS, et al., Dev Biol. 2022 Jul;487:42-56
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory